1. How to Give a Lecture Marc A. Schuckit, MD UCSD

2. Copyright Alcohol Medical Scholars Program 2 GIVING A LECTURE  Everyone can do it  Learn a style  Modify for you

3. Copyright Alcohol Medical Scholars Program 3 THIS LECTURE COVERS  Philosophy  Preparation  Slides  Delivery  Questions

4. Copyright Alcohol Medical Scholars Program 4 PHILOSOPHY  Set ~ 4 clear goals  Goal must fit audience  Needs of audience are key  10-15 min. attention span

5. Copyright Alcohol Medical Scholars Program 5 PREPARATION  Know material  Develop outline  Revise  Practice  Expect problems

6. Copyright Alcohol Medical Scholars Program 6 REVIEWING THE LITERATURE  Begin with recent paper  List topics on sheets  Go to other recent articles  Extract on sheets  Summarize complex sheets  Place in order  Fill in holes

7. Copyright Alcohol Medical Scholars Program 7 DEVELOPING AN OUTLINE I. Major topics A. Components of topics 1. Explaining components a. Details 1) Etc. II. A. 1. 2. B. 1. 2.

8. Copyright Alcohol Medical Scholars Program 8 PREPARATION  Know material  Develop outline  Revise  Practice  Expect problems

9. Copyright Alcohol Medical Scholars Program 9 SLIDES  Major topics ~ 4 key slides  Develop 2nd level slides  All slides to be  10th grade level  Understood in 10 secs  Simple  Large writing

10. Copyright Alcohol Medical Scholars Program 10 SLIDES: DON’T USE  Book tables/figures  Quotations  Too many  Overheads

11. Copyright Alcohol Medical Scholars Program 11 TYPES OF SLIDES  Label topics  Outline talk  Set mood  Focus attention  Show criteria  Draw conclusions  Show simple data

12. Copyright Alcohol Medical Scholars Program 12

13. Copyright Alcohol Medical Scholars Program 13 THE IMPORTANCE OF GENETICS IS SUPPORTED BY:  Family  Adoption  Twin

14. Copyright Alcohol Medical Scholars Program 14 VARIANCE OF RISK (Heterogeneous and Polygenic)

15. Copyright Alcohol Medical Scholars Program 15 LOW LEVEL OF RESPONSE TO ALCOHOL (LR) 1.Less Alcohol Related Change on a Challenge. 2.The Need for a Relatively High Number of Drinks for an Effect.

16. Copyright Alcohol Medical Scholars Program 16

17. SRE TIME FRAME: DRINKS 1st 5 Recent Heaviest NEEDED TO: Times 3 Mos Feel Effect Feel Dizzy or Slur Speech Stumble Fall Asleep

18. LR 60% Genetics LR Relates to Risk COA Native Americans Koreans Low LR Predicts Outcome

19. COMPLEXITIES  Environment  Heterogeneous  Polygenic

20. SEARCH FOR GENES FOR LR  Association  Linkage  Animal Models

21. GENOTYPES, LR, & ALCOHOL DEPENDENCE 5HTTGABA A  6 BOTH LL+ SS+ LL SL SS Pro/Ser Pro/Pro Pro/Ser Pro/Pro LR %ALC -.89 -.30 00 57 21 12 -1.01 -.27 71 23 -1.29 +.03 100 00

23. DOMAINS  Behavioral Undercontrol (BU)  Coping Style (WOC + DTC)  Stress(LES + Work Stress)  Social Support (SSQ N, S + SPS)  Expectancies (AEQ)  Drinking Environment (IPA + Spouse)

24. FHalc LR PEER HOME EXPECT COPE ALCOUT LR MODEL

25. LR MODEL (Kids)

26. Theoretical Gene X Environment Model

27. GABA X EXPECT

28. IMPLICATIONS FOR PREVENTION Enhance Education of Vulnerabilities Find Environmental / Psychosocial Protective Factors Specific to Risk

30. Copyright Alcohol Medical Scholars Program 30 DELIVERY  Inspect room  Stand  Use outline  State goal and structure

31. Copyright Alcohol Medical Scholars Program 31 DELIVERY  Announce transitions  Summarize along the way  Build in rests  Eye contact & revise  Watch clock  End with major points

32. Copyright Alcohol Medical Scholars Program 32 QUESTIONS  Restate question  Never get angry  Dealing with rambling Qs  Admit when don’t know

33. Copyright Alcohol Medical Scholars Program 33 OTHER TOPICS  Humor  Handouts  Boredom  Getting lost  Emergencies

34. Copyright Alcohol Medical Scholars Program 34 CONCLUSIONS  Everyone can lecture  Focus on audience  Preparation is key