1. Albuterol’s Effect on the β2-Adrenergic Receptor
Enna van den Akker

2. Albuterol Intro One in twelve Americans suffer from asthma
3.7% of Americans diagnosed with Bronchitis in the past year.
Used to increase lung function
Medicine for asthma and bronchitis
Ligand for a β2-adrenergic Receptor
Results in smooth muscle relaxation and bronchodilation

3. With Albuterol Albuterol G-Protein β2-Adrenergic Receptor
Adenylyl Cyclase
GDP
cAMP
Ca2+
ATP
GTP
Protein Kinase A
Myosin Light chain Phosphatase
Ca2+
Ca2+
Myosin Light chain Kinase K P
Calcium Channel
Calcium Activated Potassium Channel

4. Without Albuterol G-Protein β2-Adrenergic Receptor Adenylyl Cyclase
GDP
cAMP
Ca2+
ATP
GTP
Protein Kinase A
Myosin Light chain Phosphatase
Ca2+
Ca2+
Myosin Light chain Kinase K
Calcium Channel
Calcium Activated Potassium Channel

5. Conclusion Causes of bronchodilation and smooth muscle relaxation
Decreased cellular concentration of calcium
Opening of potassium channels
Inactivation of myosin light chain kinase

6. Works cited
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