1. MRI showing plaque of multiple sclerosis.

2. Left: Coronal section of cerebrum showing multiple sclerosis
Plaques at the apex of both lateral ventricles.
Right: HE/LFB stain of axial section of pons showing several
Multiple sclerosis plaques.

3. Left: Sharp edge of demyelination in MS plaque.
Right: Macrophage infiltrate and
astrogliosis in MS plaque.

4. Axial section of pons and cerebellum showing discoloration
And softening of central pontine myelinolysis.

5. Axial whole-mount section of cerebrum stained with LFB
Showing caudal-to-rostral gradient of demyelination in
adrenoleukodystrophy.

6. Loss of myelin and perivascular inflammatory infiltrate in affected
Region of white matter in adrenoleukodystrophy (HE stain).

7. Cerebral white matter showing
Globoid cells of Krabbe’s disease (HE stain).

8. Subpial collection of Rosenthal fibers
in a cerebral gyrus from an
infant who died of Alexander’s disease.