1. Cell Reproduction Meiosis aka Cell Division

2. Meiosis Cell division where one diploid cell (2n) produces four haploid (n) cells called sex cells or gametes These cells have half the number of chromosomes as a body cell of a parent

3. Meiosis vocabulary What is a gamete? Male and female sex cells; the sperm and egg What is the male gamete? Sperm; has 23 chromosomes What is the female gamete? Egg; has 23 chromosomes

4. Meiosis vocabulary… What is a zygote? A fertilized egg – has a diploid number (2n) of chromosomes What is sexual reproduction? The pattern of reproduction that involves the production and fusion of haploid sex cells What is a diploid cell? Cell containing two of each kind of chromosome from the parent

5. Meiosis vocabulary… What is a haploid cell? Cell containing one of each kind of chromosome from the parent What is an allele? Gene form for each variation of a trait of an organism. Example: gene for height can express tall or short Homologous chromosomes: Pairs of like chromosomes even though the alleles may be different – so they are not identical chromosomes – sibling variation

6. The Phases of Meiosis Meiosis I Interphase Prophase I Metaphase I Anaphase I Telophase I Meiosis II Prophase II Metaphase II Anaphase II Telophase II

7. Interphase Carries out metabolic activities of the cell Replicates its chromosomes Precedes meiosis 1

8. Prophase I Chromosomes coil up and spindle form Homologous chromosomes pair up and a four-part structure called a tetrad forms

9. During prophase I… Tightly wound tetrads get so close to one another that the genetic material from one homologous pair exchanges with the other creating new combinations of alleles in the genetic code Nuclear membrane disappears Nucleolus disappears

10. What is crossing over? Exchange of genetic material by non-sister chromatids during prophase I Results in new combinations of alleles

11. Metaphase I Tetrads line up at the equator Homologous chromosomes are lined up in pairs along the midline or equator of the cell Spindle fibers attach to the centromere on each pair The pairs are not attached to each other

13. Anaphase I Homologous chromosomes are separated and pulled to opposite poles of the cell The centromeres do not split during this phase Each new cell receives only one chromosome from each homologous pair

15. Telophase I Spindle breaks down Chromosomes uncoil Cytoplasm divided in 2 Each cell has half the genetic information from the original cell Chromosomes are still doubled containing two sister chromatid Nuclear membrane reforms Two diploid daughter cells formed

17. Meiosis II Is there an interphase in Meiosis II? No. Chromosomes do not replicate The cells go directly from meiosis I to meiosis II

18. Prophase II Spindle forms in each of the two new cells Chromosomes are still coiled as sister chromatids Nuclear membrane disappears Nucleolus disappears

19. Metaphase II Chromosomes line up at the equator of the cell Spindle fibers attach to the centromeres

20. Anaphase II Centromeres split Spindle fibers pull separated chromatids to opposite poles of the cell

21. Telophase II Spindle fibers disappear Chromosomes uncoil Nuclear membrane reforms Nucleolus reforms Cytoplasm divides Each cell now has half the chromosomes that its parents had Four daughter haploid cells are formed

23. What are the two divisions of meiosis? Meiosis I and Meiosis II Meiosis I When homologous chromosomes come together and separate Meiosis II The division that results in 4 daughter cells, each with half the chromosomes present in the original cell

24. What is genetic recombination? Genetic variation due to crossing over and random assortment How many ways can the chromosomes line up? 2

25. How do you find the total number of different kinds of sperm and egg that can be produced? Take the number of pairs and place it as the exponent with a base of 2 Example: in humans there are 23 pairs of chromosomes For sperm: 2 23 = over 8 billion For egg: 2 23 = over 8 billion

26. What is the total when fertilization occurs? 2 23 * 2 23 = 70 trillion zygotes are possible

27. What is oogenesis? Refers to the formation of the egg cell

28. What is spermatogenesis? Refers to the formation of the sperm cell

29. Practice Quiz Get out 1 sheet of blank paper. No half sheets of paper.

30. Practice quiz 1.How many cell are produced from the cell division of meiosis? 2. Does the DNA replicate itself before meiosis II? 3. What is the stage where the tetrad forms?

31. Practice quiz… 4. What are the stages of meiosis? (in order) 5. In what phase does the DNA double? 6. How many cells are produced from spermatogenesis? 7. How many cells are produced from oogenesis?