1. What do these words mean?
Analgesic
Antipyretic
Anti-inflammatory
Anti - platelet

2. What do these words mean?
Analgesic
painkiller
Antipyretic
drugs which reduce the body temperature during a fever
Anti-inflammatory
drugs which reduce inflammation
Anti – platelet
reduce platelet aggregation and thrombus formation

3. Aspirin and Quinine Lesson 12 Learning Objective:
To recall where salicin found To describe the importance and medicinal value of aspirin To describe the importance and medicinal value of quinine and where it is found

4. Aspirin Development TASK: Investigating Aspirin
Active ingredient SALICIN is found in the bark and leaves of the willow tree
Salicylic acid can be made – it is a more effective painkiller but has unwanted side effect as it irritates the lining of the stomach and intestines.
Aspirin contains a version of salicylic acid which reduces pain, but without the adverse side-effects. Aspirin:
Relieves pain
Reduces swelling in the joints and other tissues
Reduces formation of blood clots
Reduces fever
TASK: Investigating Aspirin

5. Malaria
Caused by the Plasmodium parasite
Carried by female mosquitoes

6. Symptoms
Appear between 10 days to 4 weeks after the initial bite. (In rare cases will take up to 1 year)
Benign malaria
fever (with a temperature up to 40°C)
chills
generally feeling unwell
muscular aches
headaches
diarrhoea
nausea and vomiting
Malignant malaria
similar symptoms to benign malaria plus
breathing problems
Fits
liver failure
Shock
Malignant malaria can also affect the brain and central nervous system. If it does, it will often cause this strain of the illness to be fatal.

7. Malaria hotspots – why here?

8. Quinine Development
Quinine is found in the CHICHONA bark. It kills the Plasmodium parasite and lowers body temperature
Other anti-malarial drugs such as CHLOROQUINE exist
Some strains of Plasmodium have become resistant to the drugs

9. Prevention Find out how you can prevent the spread of malaria? Nets
Removal of stagnant water
Insecticides

10. The lifecycle of the mosquito

11. Why are people living in these areas less likely to get malaria????
Sickle cell anaemia