1. Histocompatibility Committee Spring 2014

2.  Updates to Calculated Panel Reactive Antibody (CPRA)  More recent cohort used to calculate HLA and ethnic frequencies  Addition of HLA-C  Addition of required question on Waitlist ℠ for KI, K/P, PA candidates-Effective March 20, 2014  Was this candidate tested for anti-HLA antibodies? -Yes, antibodies detected -Yes, no antibodies detected -No, not tested Recently Implemented

3.  Changes to Histo Bylaws—Effective Feb. 1, 2014  Notify UNOS within 7 days of change in key personnel, ubmit a personnel change application and lab coverage plan within 30 days  Send notification to Sally Aungier (sally.aungier@unos.org)  Includes key personnel who accept additional responsibilities for more than 30 days at another histo lab  Must have qualified director, tech supervisor, and clinical consultant at all times (including periods of key personnel transition)  Must have written agreements with every affiliated OPO or transplant hospital  Agreements must contain certain elements

4. Availability of key personnel List of key personnel responsibilities delegated to other staff Documentation that qualified staff are available to perform testing (24-hour coverage if DD testing for KI, K-P, or PA) If key personnel serve multiple labs, how continuous coverage is provided at each lab served Laboratory Coverage Plan

5.  Lee Ann Baxter-Lowe Committee Chair lbaxterlowe@chla.usc.edu  Name Region # Representative Email  Gena Boyle Committee Liaison gena.boyle@unos.org gena.boyle@unos.org Questions?