1. Biology 1060 Chapter 8 Introduction to Metabolism

2. Metabolism List the kinds of chemical reactions occurring in cells and organisms Define metabolism and discuss how it is organized Differentiate between catabolic and anabolic pathways –Give an example of each

3. Energy Define energy and differentiate between kinetic and potential energy –Give examples of each State the first law of thermodynamics –Describe its meaning State the second law of thermodynamics –Describe its meaning using the term entropy Apply these laws to cells and organisms

4. Free Energy Define free energy –Discuss the equation allowing its calculation Relate ? G to spontaneous reactions Discuss chemical equilibrium using the concept of free energy

5. Exergonic and Endergonic Define and describe endergonic and exergonic reactions Discuss metabolism Explain why a cell’s metabolism never reaches equilibrium

6. ATP Describe the three types of work performed by the cell Define energy coupling –Describe the role of ATP in the cell Define phosphorylation –Describe how ATP transfers energy Describe the ATP cycle

7. Activation Energy Define activation energy –Describe its importance in chemical reactions Describe how enzymes function in the cell –Explain why this is a more appropriate mechanism than other ways to lower the activation energy barrier

8. Enzyme Specificity Describe how an enzyme functions as a catalyst Describe the changes in the substrate and enzyme as products form Discuss the active site and reversible reactions catalyzed by an enzyme

9. Enzyme Action Discuss how an enzyme helps the reaction proceed Name the factors that determine the rate of a reaction –describe the effect of each Discuss the ways in which chemicals may inhibit an enzyme

10. Control of Metabolism Define and describe allosteric regulation Define and describe feedback inhibition Discuss how the cell optimizes enzyme action

11. Questions p. 159 Evolution Connection Scientific Inquiry Science, Technology, and Society