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In Vivo Optical Imaging: Human Application?
Vassiliy Tsytsarev University of Maryland school of Medicine In this study, optical-resolution photoacoustic microscopy was used to monitor the somatosensory cortex for vascular responses to direct electrical stimulations through a cranial window.
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Glucose Metabolism Capillary Glycogen TCA TCA
Yongmei Chen and Raymond A Swanson Journal of Cerebral Blood Flow & Metabolism (2003) 23, 137–149; Astrocytes and Brain Injury
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Glucose Fluorescence Substitute: 2-NBDG
2-deoxy-d-glucose 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxy-d-glucopyranose (2-NBDG) D-glucose
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Glucose Fluorescence Substitute: In vivo imaging of epileptic activity using 2-NBDG
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Epileptic Seizures: Fluorescence Imaging
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fMRI vs NIRS
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Light Banana
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Light Banana: Oxygenation
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Main parts of experimental setup
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HITACHI: medical application
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Spectrum: T-ray
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EROS: Optical correlation of the EEG?
Evoked Response Optical Signal (EROS) (Gratton et al, 2002, 6, 7)
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T-ray imaging
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Acknowledgments Drs. Shigeru Tanaka, Hidenao Fukuyama, Kazuyuki Imamura, Ayako Ajima, Hisayuki Ojima, Minoru Kimura and Jerom Ribot – Brain Science Institute of RIKEN and Kyoto University, Japan Dr. Sonya Bahar, Director, Center for Neurodynamics, University of Missouri at St. Louis Daisuke Takeshita and Douglas Joseph Brumm – Ph.D students, Center for Neurodynamics, University of Missouri at St. Louis Song Hu, Junjie Yao, Li Li – Ph.D. student of the Washington University in St. Louis Drs Konstantin Maslov and Lihong Wang – Department of Biomedical Engineering, Washington University in St. Louis
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Thank you very much for your attention
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