1. Phospholipids and Electromagnetism in the management of autism and degenerative neurological diseases Victor A Marcial-Vega,MD www.marcialvegamd.com marcialvegamd@aol.com Orlando,Florida, 2013

9. President’s Cancer Panel Report 2010

10. Integrative Medicine Centers n Cleveland Clinic n Johns Hopkins Hospital n UCLA n George Washington University n MD Anderson Cancer Center n MSK Cancer Center n Massage, Nutrition, Acupunture, Psycotherapy

11. Integrative Medicine n Recognizes a crucial environmental role of toxins in the etiology and/or worsening of most diseases n Ex. Carbon-Petroleum based energy production, plastics, pesticides, heavy metals.

12. Heavy Metals n Present in 100% of the population n Marker of other toxins present in organism n Higgins, 2012- Parts per trillion of mercury significant (up to 1/1,000,000,000,000) significant in production of disease

13. 24 hour urine collections Puerto Rico, 2008-2012 Marcial-Vega, et al, 2013 mmmmm Metals% from 51 patients Range(ug/g creatinine) Lead100% 52/520.1 - 79.1 Mercury65% 34/520.3 - 12.30 Aluminum92% 48/520.8 - 77.4 Arsenic100% 52/521 - 105 Cadmium98% 51/520.05 - 16.09 Gadolinium71% 37/520.005 - 93.5 Nickel65% 34/520.2 - 15.39 Uranium33% 17/520.008 -.2

14. Pre and Post EDTA Calcium metalsprepost Lead1.062.2 Mercury0.552.87 Aluminum0.13177.4 Arsenic617 Gadolinium0.84478 Nickel0.910 Uranium00.183

15. PROVOCATION WITH EDTA n Conventional medicine discourages provocation because of increased toxicity n They recommend diagnosis with blood n We have found the opposite n It is both diagnostic and therapeutic under strict nutritional conditions

16. IV Push with EDTA Calcium n 245 patients n 2010-2013 n Median Age 57 n Dose range 300-3000 mg n Median 2.4 grams

17. IV Push with EDTA Calcium n 5 minute infusion/once a week n Lowering of total cholesterol, LDL 85% n Lowering of glucose levels 92% n Disappearance of joint pains 95% n More energy and sleeping better 100% n Marcial-Vega, 2013

18. Retrospective Review of a Rejuvenation Program in the Management of Cancer Victor A. Marcial-Vega, MD www.marcialvegamd.com San Juan, Puerto Rico April 2013

19. Treatment Protocol n Nutritional Supplementation n Intravenous Vitamin C (+ or - EDTA) n Ozone/Hyperthermia showers

20. Intravenous Therapy n Vitamin C 20 grams n Vitamins B1, B6(100 mg), B12 (1000ug) n Sterile water(250 cc) n EDTA 2-6 cc(3g/21cc )

21. Intravenous Therapy n Three times a week n 20 gram weekly increases until 70 grams or tolerance is reached n Dose range 50-70 grams

22. Ozone/Hyperthermia Showers n 5 days a week n 1/2 hour treatments n 98-103 degrees Fahrenheit

23. Results n Age Range 8-80 years Median 56 years n Median Follow-up 18 months n Analysis on 40 patients

24. Initial Response n More than 50% reduction of tumor n Within 3 weeks n (A) 25/33= 76% n (B) 3/5 = 60% n (C) 1/2 = 50% n Overall = 72%

25. 18 months results n No tumor after multiple recurrences 2/33 n Complete Response 6/33 n Partial 6/33 n Total 14/33=42%

26. Symptoms n Improvement in 80% first 2 weeks n Sustained at 5 months in 50%

27. Memory and Awareness n Most patients report an improvement in cognitive, memory and focusing n Brain characteristics n This is an indicator of correlation between toxins and brain function

35. n These protocols are not as effective for neurological diseases. Seemed like detoxification was not enough and tissue regeneration had to be adressed

36. Phospholipids n Plaquex n In the management of cardiovascular diseases and detoxification n Our clinic in Miami started managing and detoxing patients with IV phosphatidylcholine

37. Phenylbutyrate n Crosses the blood brain barrier n Can calm a child with self mutilation symptoms in minutes n Can resolve headaches in migraine patients n Adjunct in detoxing the brain

38. Patricia Kane, Ph. D. n Has done work managing neurological diseases with phosphatidylcholine, glutathione and methylcobalamin together with GCSF, erythropoietin, phenylbutyrate n Reversal of neurological situations doing protocol daily and up to three times a day

39. Neurological Diseases Adults n More than 85% of Alzheimer’s Disease patients will have an MRI or CT scan showing white matter changes consistent with small vessel ischemic disease. n A disease of brain toxicity n Fourth leading cause of death in Puerto Rico. 6 th in the USA

40. Alzheimer’s Disease n Gochi, Chlorella, Vitamin C and Lactobacillus n Alkalinizing Program n Intravenous phosphatidylcholine n 250-1500 mg IV Push or IV bag in D5W n MB12, Glutathione n Weekly

41. PEMF-100 n Pulsed electromagnetic frequency device n Detoxifies the cells n Reduces inflammation n Increases circulation n Increases cellular nutrient uptake n Promotes stem cell formation

42. Inspirstar n Device developed by Edward Kondrot, MD n Microcurrent Device n Wet towels around silver glove poles n Towels are placed in a sandwich technique or limb-limb, limb-trunk

43. Alzheimer’s n 25 patients n Marked improvement in 72% of the patients n 2 had no response (8%) n 20% Moderate response Phosphatidylcholine Phosphatidylcholine

44. Prognostic Factors n AGE n Performance Status

45. Prognostic Factors n Patients with Alzheimers in their 50’s have a 70%(2/3) chance of not responding and rapidly progressing to severe dementia within a year n Only 30% have responded, reversed all their symptoms and remained free of disease(1/3)

46. Prognostic Factors n If patients can carry a normal conversation and walk, they have more than 90% chance of responding favorably to this protocol n If they cannot carry a normal conversation and not walk well, they have a more than 90% chance of not responding

47. Dementia n 10 patients n Marked improvement in most of their cognitive capacities n Improvement in socialization and orientation to place n Last aspect to improve-Short term memory

48. Parkinson’s Disease n 5 patients n Steady improvement in the first 2 months in 3/5 n 1 patient –No change n 1 patient-Dramatic improvement and reversal of all symptoms with PTC and pulsed electromagnetic frequency n All patients now get PEMF

49. Zoster Neuropathy n Poor results in 7 patients treated with intravenous vitamin C and hydrogen peroxide n 1 patient treated with Inpirstar had near complete resolution of their symptoms after 6 treatments

50. Herpes Neuropathy Beguinning of a cold sore sensation with neuropathic severe pain from the lip up by lower outer jaw. Attacks typically start like this, pain worsens over 24 hours and the blister appears. After one hour of microcurrent, pain is gone and no blister appeared

51. Chemotherapy Induced Neuropathy n Cisplatin, Carboplatin associated n Very painful n Feet and hands n Does not respond well to analgesics

52. Randomized Study Glutathione n Stomach Cancer Patients n Randomized to IV glutathione before chemotherapy versus none n Placebo group-All developed neuropathy n Treated group 10% developed neuropathy n Also, non-statistically significant difference in survival

53. Neuropathy n Management with phosphatidylcholine n 10 patients n Weekly n Improvement in all patients in the first two treatments n Complete Resolution of pain in 8 pts. n The earlier the better

54. ALS n 8 patients n One-EDTA, IVC, H2O2-no response. Died in less than a year n 2 more with PTC-No response n 1 Pt. with 3x/day tx 15 txs. Week n First week regained vocal cord and swallowing movement

55. ALS n Stopped treatment after 3 months and deteriorated n One patient was stable for one year speaking and walking. Died from a fall n One patient improved and spasticity markedly improved with PTC and PEMF

56. ALS n Latest 2 patients n #1 in less than 2 weeks could understand previously unintelligible speech. Swallowing better. n Improved pulmonary function studies n #2 Could move extremities better in 2 weeks n Both had daily treatment

57. Side Effects n Temporary (minutes) dizziness-2 n Extravasation and burning that would last days, weeks and sclerose veins temporarily 4% n Months of sclerosing 3 patients

58. AUTISM n 1:37 in Puerto Rico n 1:50-75 in the USA n No more figures presented in CDC website since 2008 n Rapidly rising epidemic n Maybe related to aluminum and mercury in vaccines

59. AUTISM n 75 patients n 7 Did not complete treatment n Of the 68 remaining patients n Analysis n 75% trigered at 18 months of age related to vaccine booster doses

60. AUTISM n Eliminate sugar, complex carbohydrates n Start nutritional alkalinization n Intravenous phosphatidylcholine n 250-1000 mg a week n Glutathione IV 400 mg a week n Methylcobalamin 1000 ug n Folic acid 4 mg

61. AUTISM n After 10-20 Weekly treatments n IV Phenylbutyrate 100-400 mg in 100 cc/d5w n Continue if there was a steady improvement n Side effects- Rash in 2 patients. Glutathione eliminated in them and it resolved. They were both allergic to eggs

62. RESULTS

67. Frederick’s Ataxia n Hereditary disease n Poor prognosis n Progressive Degenerative Disease n 2 sisters 14, 16 years old n 5 treatments so far n Improvement in gait, fine motor movements and energy levels

68. CONCLUSIONS n Phospholipid therapy reverses the pathologic features of autism and other neurological diseases n Phenylbutyrate seems to detoxify the brain and has a calming effect in all patients n One to two years of therapy may reverse all symptoms completely

69. CONCLUSIONS n Minimal side effects (allergic reaction and itching in one patient) n Worsening of symptoms n Hypoglicemia that is prevented by eating before therapy