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Lectures on respiratory physiology Diffusion. Swim bladder of a fish.

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Presentation on theme: "Lectures on respiratory physiology Diffusion. Swim bladder of a fish."— Presentation transcript:

1 Lectures on respiratory physiology Diffusion

2 Swim bladder of a fish

3 Fick’s law of diffusion through a tissue sheet

4 Very thin blood-gas barrier

5 Electron micrograph of pulmonary capillary

6 High power view of blood-gas barrier

7 Fick’s law of diffusion through a tissue sheet

8 Kinetic theory of gases

9 Fick’s law of diffusion through a tissue sheet

10 Diffusion and perfusion limitations

11 PARTIAL PRESSURE, mm Hg CO-Hb DISSOCIATION CURVE SATURATION, % CO O2O2

12 Diffusion and perfusion limitations

13 Very thin blood-gas barrier

14 Thickened blood-gas barrier

15 Time courses of P o 2 in the capillary

16 Measurement of Diffusing Capacity

17 Single breath method for D CO

18 Electron micrograph of pulmonary capillary

19 Reduced Hb O 2 solution Mixing Chamber t Spectro Photometer HBO 2 % 100 0 0.10.2 time (sec) Measurement of the rapid reaction of O 2 with Hb

20 The two components of D L

21 Is the transfer of CO 2 ever limited by diffusion?


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