1. 4/10 Daily Catalyst Pg. 48 DNA Structure
1. Create a simile for DNA.
2. Who were the three scientists involved with the discovery of the structure of DNA?
3. What is the technique utilized to uncover the structure of DNA?
4. Why is DNA stored in the nucleus?

2. 4/10 Class Business Pg. 48 DNA Structure
Quiz #11 on Friday
Intro to DNA
Unit 4 Extra Credit due Monday, April 13th
Find an article on genetics or genetic disease and write a half page summary/opinion on the article.
Print out the article and staple your half sheet to the article.
Quiz #12 next Friday
DNA test 4/21

3. 4/10 Agenda Pg. 48 DNA Structure
Daily Catalyst
Class Business
Objective
DNA structure notes
Quiz #11 DNA

4. 4/10 Objective
We will be able to construct scientific explanations that use the structures and mechanisms of DNA and RNA to support the claim that DNA and, in some cases, that RNA are the sources of heritable information.

5. Essential Questions: Who discovered the structure of DNA?
What is the structure of DNA?
How does the structure of DNA relate to its function?
How does the structure of DNA allow DNA to be the source of heritable information?

6. DNA video clip
**Pay close attention to the description of DNA’s structure**

9. Key Point #1: Vocabulary
Monomer
Polymer
One part
Many parts
DNA is made of nucleotides. We can think of a nucleotide as the building blocks that come together to form the struture-DNA.

10. What are all the parts that make up this?

11. Nucleotide Key Point #2: A nucleotide is one part (monomer)
Multiple nucleotides make up DNA

12. Key Point #3: Nucleotides 1 Sugar 1 Phosphate 1 Base
The building blocks of DNA are nucleotides. Every nucleotide is made of 3 parts- sugar, phosphate, and base. What does the term “deoxyribose” mean?
1 Sugar
1 Phosphate
1 Base

13. The sugar:
Deoxyribose
What does that mean?
De:
Without
Oxy:
Oxygen

14. The phosphate
Plain and simple
Phosphate group

15. The bases Every nucleotide has 1 base, but there are 4 to choose from:
4 nitrogenous bases
A,T,C, & G

16. Phosphate
Sugar
Bases

17. The backbone is made up of _________ and ___________.
Key Point #4:
The backbone is made up of _________ and ___________.
Phosphodiester bonds hold the backbone together.
Strong, covalent bond
SUGAR
PHOSPHATE
Hydrogen

18. Key Point #5: The middle of the ladder are the bases.
The bases are held together by _________ bonds.
HYDROGEN

19. Complementary Base Pairing
The two sides of the “ladder” are held together by the hydrogen bonds between the bases.
The bases are sooo picky and will only pair up with a certain base.
Key Point #6: Complementary Base Pairing:
A-- T
C-- G

20. Structure
In 1953 Watson, Crick, and Franklin discovered DNA had the shape of a double helix.
The DNA is a double helix
Double: two strands
Helix: twisted.
Examples?
In 1952, two scientists discovered the shape of DNA. They gave the name the double helix

21. Key Point #7: How does DNA get its twisted shape?
KP #7: The hydrogen bonds between the bases pull so tightly on one another that it causes the DNA to twist!
Turn and talk

22. Do not forget!
Complementary Base Pairing:
A—T
C—G

23. Tell me what ya know! What are the 4 kinds of bases found in DNA?
Thymine (T)
Cytosine (C)
Adenine (A)
Guanine (G)
Describe Watson and Crick’s model of DNA.
A double helix
AT GC
Double helix, twisted ladder

24. Tell me what ya know!
If a DNA strand has 34 Guanine bases, how many Cytosine's are there? WHY?
34, because all 34 Guanine’s need to pair up with 34 Cytosine’s
What is the purpose of DNA?
To hold our genetic information
34, base pairs
To hold our genetic informaiton

25. Tell me what ya know!
If you have the bases TATGA, what are the correct DNA base pairs?
T A T G A
A T A C T
G A C C T A G
C T G G A T C
ATACT

26. DNA Model Color the sugars- red Color the phosphates- green
Directions: On page 49 DNA model, create a DNA strand from the pieces given to you. Glue the model to page 49.
Color the sugars- red
Color the phosphates- green
Color the thymine- yellow
Color the adenine- blue
Color the guanine- purple
Color the cytosine- orange

27. Quiz #11
Directions: Silently and independently complete the quiz. Turn your quiz into the basket when you are finished. Time: 10 minutes Noise: 0 (SILENT)

28. 4/10 Homework
Directions: Fill in the chart about RNA and DNA on notebook page 50 RNA.
Location
Function
Structure
Bases
Sugar groups
DNA
RNA