1. Introduction to Oral Cancer Gene Database ．資訊三 朱民晃 B92902025 ．資訊三 陳皓遠 B92902062

2. The Tumor Gene Family Databases

3. Introduction(1/2) http://www.tumor-gene.org/ http://www.tumor-gene.org/ The Tumor Gene Family of Databases contains information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor supressor genes. The Tumor Gene Family of Databases contains information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor supressor genes. These databases are designed to for biomedical researchers who work with tumor genes. These databases are designed to for biomedical researchers who work with tumor genes.

4. Introduction(2/2) Tumor Gene Database Tumor Gene Database Breast Cancer Gene Database Breast Cancer Gene Database Oral Cancer Gene Database Oral Cancer Gene Database

5. Oral Cancer Gene Database What information dose the database contain? What information dose the database contain? This database contains information about genes which are targets for cancer- causing mutations in oral cancers. This database contains information about genes which are targets for cancer- causing mutations in oral cancers. List of Oral Cancer Genes List of Oral Cancer Genes A member of the Tumor Gene Database family A member of the Tumor Gene Database family http://www.tumor-gene.org/Oral/oral.html http://www.tumor-gene.org/Oral/oral.html

6. Get the list of Oral Cancer Genes (1/2) Click here to get information of the Oral cancer list

7. Get the list of Oral Cancer Genes (2/2) List of Oral Cancer Genes List of Oral Cancer Genes

8. How to search the database (1/4) Key in a Gene Name or a word in a fact you want to search

9. How to search the database (2/4) Click the “ Search ” button to search

10. How to search the database (3/4) Get 1 match of the gene “ BAX ” Click the hyperlink of “ BAX ”

11. How to search the database (4/4) OMIM ID Number OMIM ID Number of NCBI

12. What can we get ? (1/2) Cell Type Distribution Cell Type Distribution Clinical Clinical Complementation Complementation Function Function Gene Frequency (Tumors) Gene Frequency (Tumors) Protein Binding Protein Binding Regulation Regulation

13. What can we get ? (2/2) Flag Link to Citation of NCBI

14. Flags Primary Fact from a Full Paper Primary Fact from an Abstract Secondary Fact from a Full Paper Secondary Fact from an Abstract Primary Fact from a Review Secondary Fact from a Review Unknown

15. Link to GeneCards (1/2) Click here to link to GeneCards website

16. Link to GeneCards (2/2)

17. NCBI – OMIM (1/4) Remember to choose “ OMIM ” *600040, the OMIM ID Number

18. NCBI – OMIM (2/4) Click here; go to the OMIM homepage. Click “ FAQ ” to get details about OMIM

19. NCBI – OMIM (3/4) What do the symbols preceding a MIM number represent?

20. NCBI – OMIM (4/4) Ex: An asterisk (*) before an entry number indicates a gene of known sequence.

21. Conclusion We can search the information about oral gene in the database. We can search the information about oral gene in the database. We can get the OMIM ID about the gene in the NCBI database. We can get the OMIM ID about the gene in the NCBI database. We can get the list of genes in the oral database. We can get the list of genes in the oral database. We can link to GeneCards website. We can link to GeneCards website.

22. Thanks for your attention.