1. Issues in developing NDAR autism ontology Samson Tu Stanford Center for Biomedical Informatics Research 2007-11-19 conference call

2. Strategies for extending BIRLEX ontology Define concepts derived from literature DSM-IV concepts (capabilities) Hus 2007 concepts (phenotypes) Model assessment results NDAR codebook Relate concepts to assessment results using OWL DL or SWRL rules

3. Model CodeBook as assessment result

5. Issues in using BIRNLex Versions and inconsistencies Clarification of concepts Phenotype under _birnlex limbo class Phenotype/behavior/developmental capability/, assessment/assessed results/assessment instrument Distinction between generically and specifically-dependent classes Need for community input

6. BIRN Mediator issues Current definitions written in OWL DL or SWRL Develop user-level tools Translation to BIRN Mediator? Need BIRN Mediator query language Need to understand how ontology is used Low repetitive sensory motor activity adi_2003((?a) ∧ dbaes_unsensfailC4(?a, ?rsma1) ∧ cbaes_unsensfailC4(?a, ?rsma2) ∧ intbehav_cunsens(?a, ?rsma3) ∧ intbehav_eunsens(?a, ?rsma4) ∧ intbehav_cabinr(?a, ?rsma5) ∧ intbehav_eabinr(?a, ?rsma6) ∧ swrlb:add(?sum, ?rsma1, ?rsma2, ?rsma3, ?rsma4, ?rsma5, ?rsma6) ∧ swrlb:lessThanOrEqual(?sum, 4) → LRSMA(?a)