1. “CURRENT VIEW AND FUTURE DIRECTIONS ” Alzheimer’s disease Therapy Initiative (ADTI)

2. ADTI Many things we know about conducting research with older adults have been reaffirmed – Explanations must be clear and provided in a manner that people find understandable – Caregivers often appreciate talking to someone about their situation Some areas have been challenging

3. ADTI Overall, positive effects of ChEI medications are suggested through our results Consistent with previous research Small effects, but clinical relevant Reflect “real” life utilization of these medications

4. Collection of Unique Data Information about trends in utilization are emerging Use of novel measures that capture dimensions of benefit not tapped in conventional measures Treatment outcomes beyond clinical trial duration

5. Future Directions and Opportunities ADTI program provides an opportunity to utilize what we have learned and how that may be translated into future coverage policy