1. CHROMOSOMES Chromosome-before a cell divides it copies all the DNA (replication) and then coils it into Chromosomes

2. CHROMATIDS CHROATIDS- One side of the chromosome. Each side is the same. (One of the copies of the DNA)

3. CENTROMERE CENTROMERE- Point where the two chromatids are attached to each other.

4. HUMANS HAVE 23 PAIRS OF CHROMOSOMES

5. KARYOTYPE- A PICTURE OF A HUMANS CHROMOSOMES ARANGED BY SIZE. These are used to test for Chromosomal Disorders in Unborn Babies.

6. TWO TYPES OF CHROMOSOMES THE FIRST 22 ARE CALLED AUTOSOMES WHICH ARE THE SAME FOR BOTH MALES AND FEMALES THE LAST PAIR ARE CALLED SEX CHROMOSOMES AND THEY DETERMINE GENDER XY= MALE XX= FEMALE

7. Down syndrome (extra 21 st ) Trisome X (Extra X Chromosome) Cri du chat (Missing piece of 5 th Chromosome) Digeorge Syndrome (Missing piece of 22 nd chromosome)

8. DNA REPLICATION -TAKES PLACE DURING “S” PHASE OF THE CELL CYCLE 3 STEPS 1.ENZYMES “DNA HELICASE” BREAKS HYDROGEN BONDS TO “UNZIP” THE DNA.

9. STEP 2- ENZYME “DNA POLYMERASE” MOVES ALONG THE REPLICATION FORKS ADDING NITROGEN BASES (A,C,T,G)

10. STEP 3 TWO COMPLETE DNA STRANDS ARE FORMED. EACH STRAND IS IDENTICAL

11. The replication process usually takes place on many segments of the DNA at the same time. This speeds up the process. http://www.youtube.com/watch? v=teV62zrm2P0 http://www.youtube.com/watch? v=cDlKrLJjRlY&feature=related http://www.youtube.com/watch? v=teV62zrm2P0 http://www.youtube.com/watch? v=cDlKrLJjRlY&feature=related

12. INTERPHASE G1=Growth Phase 1, Normal cell function S=Synthesis Phase, Copy the DNA G2=Growth Phase 2, Compress DNA into Chromosomes, prepare for cell division.

13. MITOSIS P= Prophase, Chromosomes become visible and nuclear envelope breaks down M=Metaphase, Chromosomes line up in the middle A= Anaphase, Chromosomes get pulled apart cells

14. Mitosis Continued T= Telophase, Chromosomes bunch at the poles of the cell and it begins to split Cytokinesis- Two new daughter cells are formed and new cytoplasm is formed to make two adult

15. Interphase Can be broken into G1, S and G2

16. Prophase Chromosomes are formed The nuclear envelope breaks down

17. Metaphase Chromosomes line up along the “equator” of the cell

18. Anaphase Chromatids are pulled apart by the spindle fibers and move toward the poles of the cell.

19. Telophase Chromosomes reach the poles and the cell builds a cell membrane/wall down the middle of the cell

20. Cytokinesis New daughter cells replace organelles and grow into new adult cells which return to Interphase