1. Genetics Shireen Rudina

2. First: A review of Mendel’s Laws 1.Dominance 2.Law of Segregation- one allele from each parent 3.Law of Independent Assortment- each trait acts independently

3. Human Mendelian Traits GENETIC TRAITDOMINANTRECESSIVE

4. How about the rest? 1.Multiple alleles: blood type IAIA Type A blood IBIB Type B blood iType O blood IAIAIAIA Type A I a iType A IBIBIBIB Type B I B iType B IAIBIAIB Type AB iiType O blood Codominance

6. Question: A mother is Type A, and her child is type O 1.What is the child’s and mother’s phenotype? 2.There are two men claiming to be the father: one is Type B, and the other is Type AB. Which one is the father?

7. How about the rest? 2. Multiple genes for one trait

8. Sex Chromosomes: X and Y

9. Pedigree Method of following a trait down generations

10. Analyzing Pedigrees

11. Tay-Sachs Disease: Simple genetic trait

12. Tay-Sachs: A recessive disease Nervous system and brain rapidly deteriorate Children generally die by age 4 Carriers are crucial

13. If daughter A marries someone with the trait, what is the probability that their child will be affected? ? A

14. Replication

15. Materials

16. Replication process

17. Semiconservative Replication