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Published byCoral Phillips Modified over 9 years ago
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Everything in your body is a protein, or is MADE by a protein! Insulin Actin & Myosin Melanin Elastin Keratin Hemoglobin Heparin
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44 letters in RNA’s genetic “alphabet” AA C U G 220 letters in protein’s polypeptide “alphabet” HHow to get between the two? TTranslation! 3
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Begin in the middle and work your way out Example: U A C Tyrosine! p303 in your book 5
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CAG Glutamine AAA Lysine GGA Glycine GGU Glycine UUC Phenylalanine 6
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AUG Methionine OR “start” UAAUAGUGA “Stop” codons Act like the period at the end of a sentence. 8
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We know HOW to put it together, but what will actually assemble that protein? The ribosome ribosome is our protein assembly factory! ribosome = 9 Ribosome.avi
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proteins During translation, the cell uses information from mRNA to produce proteins tRNA “Knowing” which codon goes to each amino acid is the job of tRNA 10
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Each tRNA molecule has the following: Amino acid Amino acid attached to one end Region of three unpaired bases at other end ▪ (What would you call the opposite of a codon?) ▪ Anticodon! ▪Anticodon bases are complementary to one of the mRNA codons Anticodon 11
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On the ribosome, the tRNA begins binding to its appropriate site on the mRNA ribosome amino acid 13
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The next tRNA molecule binds to the next codon on the mRNA The ribosome now links those two amino acids with a peptide bond The ribosome also breaks the first tRNA-aa bond 14
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ribosome mRNA tRNAprotein 17
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The polypeptide (protein) chain continues to grow until a stop codon is reached (UAG, UGA, UAA) When it reaches a stop, the polypeptide chain is released into the wild 18 I wonder how much $$ the government spent so I can eat bamboo for 14 hours…
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ribosome mRNA tRNA 19
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