1. NMR Practice: C 4 H 10 O Given a molecular formula and an NMR spectrum, what is the structure of the compound? 2 H 3 H

2. NMR Practice – C 6 H 12 O 2 integral ratio 1 : 3.0

3. NMR : C 4 H 8 O 2 q t 3 H2 H3 H

4. Common Patters for Proton NMR 1. triplet (3H) + quartet (2H) 2. large double (6H) + muliplet 3. large singlet (9H), ~1 ppm 4. multiplet ~7.2 ppm (4-5H) 5. singlet 3.5 ppm (3H) 6. singlet 2.1 ppm (3H) ethyl group isopropyl t-butyl group aromatic ring -OCH 3 group H 3 C-C=O (methyl ketone)

5. NMR Spectrometer - schematic

6. 6 C 4 H 7 ClO 2

7. NMR : C 10 H 14 4 H m 6 H d 3 H s 1 H m

9. 9 1 H NMR : C 6 H 12

10. 10 1 H NMR : C 5 H 12 O (doublet) br

11. 11 1 H NMR : C 5 H 10 O

12. 1 H NMR : C 9 H 10 3 H doublet J = 8 Hz 1H 3H 2H 11 Hz