Presentation is loading. Please wait.

Presentation is loading. Please wait.

1 Influenza activity in the Southern Hemisphere Ian Barr WHO CC for Reference & Research on Influenza Melbourne www.influenzacentre.org The Melbourne WHO.

Published byArthur Hoover Modified over 9 years ago

Similar presentations

Presentation on theme: "1 Influenza activity in the Southern Hemisphere Ian Barr WHO CC for Reference & Research on Influenza Melbourne www.influenzacentre.org The Melbourne WHO."— Presentation transcript:

1 1 Influenza activity in the Southern Hemisphere Ian Barr WHO CC for Reference & Research on Influenza Melbourne www.influenzacentre.org The Melbourne WHO Collaborating Centre for Reference and Research on Influenza is supported by the Australian Government Department of Health and Ageing.

2 Recap on the 2010 Australian season More normal “Influenza” season –High levels of vaccination/exposure to H1N1pdm pre-season –Season began in June-July (2009 May-June) –Peaked in September (2009 Aug) –Late season cases seen in Dec 10 and Jan 11 Characteristics of season –Mainly Pandemic H1N1 viruses in Aus/ (& NZ) –Milder than 2009 season –Fewer admissions to ICU and deaths – Some vaccine breakthroughs recorded

3 Pandemic H1N1 severity up to November 5 2010 Australian Influenza Surveillance Report

4 Influenza vaccines used in Australia and NZ in 2010 H1N1pdm – A/California/7/2009 –(circulating strain: A/California/7/2009-like) H3 – A/Perth/16/2009 (circulating strain: A/Perth/16/2009-like) B - B/Brisbane/60/2008 (B/Victoria lineage) (circulating strain: B/Brisbane/60/2008-like – B/Victoria lineage)

5 Vaccine breakthroughs in 2010 in Australia Pandemic H1N1 2009 cases –Outbreak at HMS Cerebus (Victoria) in October 2010 –>30 cases (24 influenza proven positive H1N1pdm) –First 30 hospitalized (precautionary), no deaths, ICU –All vaccinated (?seasonal or pandemic) –Formed a distinct genetic clade (only one other virus seen in this group from Canberra) –Unable to determine antigenic characteristics as only RNA available H3N2 cases –Multiple reports (Nov/Dec) from Qld aboriginal settlements eg Townsville –? Hospital admissions, ? ICU, ? deaths –All vaccinated with 2010 seasonal vaccine –Genetically fell into A/Perth/10/2010 group (same as most Aus, H3’s) –Antigenically similar to A/Perth/16/2009 viruses (ie vaccine strain) B cases –None reported –n

6 Google flu trends mapping world influenza As at 3.6.11 www.google.org/flutrends www.google.org/flutrends Sth Hemisphere 7 Sth American Sth Africa Australia New Zealand

7 Google flu trends Australia and NZ As at 3.6.11 www.google.org/flutrends

8 Google flu trends South Africa As at 6.6.11 www.google.org/flutrends

9 Also now Google Dengue Trends As at 6.6.11 www.google.org/fdenguetrends Brazil Brazilian data Google Dengue trends Currently: Brazil Bolivia Indonesia India Singapore

10 ILI in Australia (2008-11)

11 ILI in NZ (2009-11) Source: ESR: Influenza Weekly Update 23-29 May 2011

12 Lab confirmed influenza cases in Australia 2005-11 (NNDSS) November 2010-May 2011 x4 influenza cases of 2010

13 Flunet data for Southern Hemisphere

14 Samples types received by Melbourne CC YearOCSVirus Isolates Ratio Isolates:OCS 20062218023.6 200744013553.1 200828014135.1 2009194412100.62 2010123510130.82 20112783691.32

15 Influenza viruses received and analysed at WHO CC for influenza 1.1.2011 – 31.5.2011 Type B Type A(H3) Type A(H1) Countries supplying samples in 2011 n=393 n=3 n=25 n=18 n=6 Pandemic (H1N1) 2009 n=27 n=16

16 A/California/7/2009 - Vaccine strain A/Brisbane/70/2011-like Main group in 2011 A/Christchurch/16/2010-like Main group in 2010 A/Perth/30/2011-like Regional group in 2011 H1N1pdm HA genes

17 A/Perth/16/2009 - Vaccine strain A/Perth/10/2010-like Main group in 2010-11 A/Victoria/2008-like Common in 2010 A/Perth/16/2009-like Few viruses in 2010 0.01 SriLanka/7/10 May Nauru/17/11 Feb Guadeloupe/202/10e Aug Victoria/552/10 Aug Victoria/506/11 Jan Victoria/650/10 Oct Brisbane/1/11 Jan Singapore/630/10 May vax Singapore/616/10 Jul vax Perth/49/10 Aug cdc Wisconsin/15/09e Jun Brisbane/217/10 Aug SriLanka/9/09 Jul Townsville/105/10 Nov Townsville/34/11 Feb SuratThani/269/10 Mar Victoria/103510 Oct NewYork/05/10cdc Mar 11S0802 Sep Brisbane/210/10e Singapore/11/11 Jan Perth/501/10e May Brisbane/220/10e NewCaledonia/2/11 Feb Chrischurch/25/10 Aug Victoria/210/09e Jun cdc Bolivia/317/10 May Alaska/5/10e Aug Nothaburi/488/10 Aug cdcMaine/02/10 Dec VICTORIA/208/09e Jun Perth/56/10 Aug Brisbane/258/10 Oct Singapore/516/10 Apr Fiji/52/10 Dec Townsville/3/11 Jan PERTH/16/09e Apr WestSepik/12/09 Aug SthAuckland/15/10 Jul Darwin/6/11 Jan Brunei/204/10 Nauru/19/11 Feb PortMoresby/2/09e Jun Townsville/60/10 Philippines/5229/10 Nov Nauru/5/11 Jan Canberra/11/10 Aug Townsville/87/10e Nov cdc Italy/540/10 May Victoria/1031/10 Oct Christchurch/1/11 Feb Victoria/8/10e Aug PHILIPPINES/16/09 Mar Singapore/521/10 Apr Townsville/7/11 Jan Kiribati/6/09 Jul Sydney/13/10 Aug Iowa/19/10e Dec SriLanka/3/10 Jul Brunei/203/10 Brisbane/253/10 Sep NewCaledonia/3/11 Feb Tasmania/2/11 Feb Townsville/97/10vax Dec Bangkok/132/09 May Johannesburg/50/10 Jul BRISBANE/10/07e Feb cdc Panama/307149/10 Jun NewCaledonia/4/11 Feb Darwin/14/11 Feb NewCaledonia/5/11 Feb cdc Iowa/07/10 Jul Arizona/13/10e Jun Townsville/20/11 Jan Cambodia/1/10 Jun Townsville/100/vax Dec PERTH/10/10e Brisbane/31/10 Jul Fiji/41/10 Nov Canberra/20/09 Jul Canberra/2/10 Jun Townsville/98/10 Dec cdc Honduras/6065/10 Apr 2010 H3 Consensus Singapore/13/11 Jan SuratThani/116/10 Feb Brunei/208/10 Victoria/500/11 Jan Townsville/93/10 Dec Victoria/1034/10 Oct Singapore/512/10 Apr Victoria/563/10e Chrischurch/49/10 Sept RhodeIsland/1/10e Jan Cambodia/15/09 Jun Victoria/4/10 May Townsville/106/10 Nov Townsville/48/11 Mar BRISBANE/11/10e May Townsville/104/10 Nov Fiji/38/10 Oct cdc Kenya/1632/10 Apr Perth/673/09 Nov Christchurch/3/11 Feb cdcWyoming/09/10 Dec Townsville/117/10vax Dec Nauru/3/11 Jan Newcastle/4/10 Jun Townsville/92/10vax Dec Perth/324/09 Jul Chuuk/3/09 Jun Darwin/25/11 Feb WestSepik/20/09 Sep Christchurch/50/10 Sep cdc Alabama/5/10 Jul Singapore/534/09 Nov Tasmania/8/09 Jun Townsville/102/10 Nov Victoria/1201/10vax Sep Singapore/617/10 jul Townsville/86/10 Nov Brisbane/252/10 Sept SthAustralia/414/10 Oct Brisbane/100/09 Jul H3 4May11 H3N2 HA genes

18 B Viruses 2010-2011 Virus type20112010 B/Brisbane/60/2008-like52387 B/Brisbane/60/2008-like Low Reactor 120 B/Malaysia/2506/2004-like116 B/Malaysia/2506/2004-like Low Reactor 050 B/Florida/4/2006-like13 Low Reactor 614

19 Summary of Southern Hemisphere influenza activity in 2011 2011 early in the SH season so far (peaks June-August) Increased out of season activity in Australia in early 2011 Increased H3N2 activity in 2011 vs 2010 in Australia –Mostly A/Perth/10/2010 genetically, still A/Perth/16/2009-like antigenically Pandemic H1N1 still common –Mostly A/Brisbane/70/2011 genetically, still A/California/7/2009-like antigenically Few B viruses (mainly B/Brisbane/60/2008-like – B/Victoria lineage) Currently 100% of H3N2H1N1pdm viruses are adamantane resistant Low levels of neuraminidase inhibitor resistance –<1% viruses currently oseltamivir (Tamiflu) resistant – mainly treatment/prophylactic use Little activity in NZ, Sth Africa or Sth America so far 2011 vaccine match so far so good……………….

Download ppt "1 Influenza activity in the Southern Hemisphere Ian Barr WHO CC for Reference & Research on Influenza Melbourne www.influenzacentre.org The Melbourne WHO."

Similar presentations

INFLUENZA DIVISION U.S. Influenza Surveillance Update, 2008-9 Season Joseph Bresee, MD Epidemiology and Prevention Branch, Influenza Division, CDC VRBPAC.

INFLUENZA DIVISION U.S. Influenza Surveillance Update, Season Joseph Bresee, MD Epidemiology and Prevention Branch, Influenza Division, CDC VRBPAC.
Influenza Surveillance

Influenza Surveillance
Characterization of human influenza virus circulation in Cambodia 2006-2010 and impact for national public health policies. Ly Sovann, MD, DTMH, MCTM Philippe.

Characterization of human influenza virus circulation in Cambodia and impact for national public health policies. Ly Sovann, MD, DTMH, MCTM Philippe.
Wrap-up of Day 1. Plenary One: Regional and Global Update Update of global situation and response to pandemic (H1N1) 2009 - Dr Wenqing Zhang Regional.

Wrap-up of Day 1. Plenary One: Regional and Global Update Update of global situation and response to pandemic (H1N1) Dr Wenqing Zhang Regional.
CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION Influenza Surveillance in Mainland of China Yuelong Shu Chinese National Influenza Center National Institute.

CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION Influenza Surveillance in Mainland of China Yuelong Shu Chinese National Influenza Center National Institute.
Line Efficiency     Percentage Month Today’s Date

Line Efficiency     Percentage Month Today’s Date
Lisa Grohskopf, MD, MPH Medical Officer Influenza Division Centers for Disease Control and Prevention U.S. Influenza Surveillance National Center for Immunization.

Lisa Grohskopf, MD, MPH Medical Officer Influenza Division Centers for Disease Control and Prevention U.S. Influenza Surveillance National Center for Immunization.
Unit Number Oct 2011 Nov 2011 Dec 2011 Jan 2012 Feb 2012 Mar 2012 Apr 2012 May 2012 Jun 2012 Jul 2012 Aug 2012 Sep 2012 1 2 3 4 5 6 (3/4 Unit) 7 8 Units.

Unit Number Oct 2011 Nov 2011 Dec 2011 Jan 2012 Feb 2012 Mar 2012 Apr 2012 May 2012 Jun 2012 Jul 2012 Aug 2012 Sep (3/4 Unit) 7 8 Units.
Influenza Vaccine Manufacturing Industry perspective for 2013-2014 influenza vaccine supply VRBPAC, 27 February 2013 The FDA CBER requested this annual.

Influenza Vaccine Manufacturing Industry perspective for influenza vaccine supply VRBPAC, 27 February 2013 The FDA CBER requested this annual.
Influenza Virus Vaccine 2013-2014 Strain Selection Vaccines and Related Biological Products Advisory Committee (2/27/2013) Jerry P. Weir, Ph.D., Director.

Influenza Virus Vaccine Strain Selection Vaccines and Related Biological Products Advisory Committee (2/27/2013) Jerry P. Weir, Ph.D., Director.
Influenza Virus Vaccine 2014-2015 Strain Selection Vaccines and Related Biological Products Advisory Committee (2/28/2014) Jerry P. Weir, Ph.D., Director.

Influenza Virus Vaccine Strain Selection Vaccines and Related Biological Products Advisory Committee (2/28/2014) Jerry P. Weir, Ph.D., Director.
Influenza Vaccine Manufacturing Industry perspective for 2012-2013 influenza vaccine supply VRBPAC, 28 February 2012 The FDA CBER requested this annual.

Influenza Vaccine Manufacturing Industry perspective for influenza vaccine supply VRBPAC, 28 February 2012 The FDA CBER requested this annual.
INFORMATION FOR THE VACCINE AND RELATED BIOLOGICAL PRODUCTS ADVISORY COMMITTEE CBER, FDA FEBRUARY 22, 2010 Nancy J. Cox, Ph. D Director WHO COLLABORATING.

INFORMATION FOR THE VACCINE AND RELATED BIOLOGICAL PRODUCTS ADVISORY COMMITTEE CBER, FDA FEBRUARY 22, 2010 Nancy J. Cox, Ph. D Director WHO COLLABORATING.
Influenza Virus Vaccine 2011-2012 Strain Selection Vaccines and Related Biological Products Advisory Committee (2/25/2011) Jerry P. Weir, Ph.D., Director.

Influenza Virus Vaccine Strain Selection Vaccines and Related Biological Products Advisory Committee (2/25/2011) Jerry P. Weir, Ph.D., Director.
Texas Influenza Surveillance Lesley Bullion Influenza Surveillance Coordinator Infectious Disease Control Unit.

Texas Influenza Surveillance Lesley Bullion Influenza Surveillance Coordinator Infectious Disease Control Unit.
Update of Antiviral Resistance in Seasonal and Pandemic Influenza Viruses 3 rd NIC Meeting, Beijing, China August 18-20 th 2009 Aeron Hurt WHO Collaborating.

Update of Antiviral Resistance in Seasonal and Pandemic Influenza Viruses 3 rd NIC Meeting, Beijing, China August th 2009 Aeron Hurt WHO Collaborating.
 A worldwide epidemic of a disease  Epidemic = increased number of cases from a disease  Pandemics have occurred from › Bacteria – cholera, Tuberculosis,

 A worldwide epidemic of a disease  Epidemic = increased number of cases from a disease  Pandemics have occurred from › Bacteria – cholera, Tuberculosis,
State Health Officer Webcast, February 27, 2015 Wisconsin Division of Public Health Wisconsin Department of Health Services Thomas Haupt Influenza Surveillance.

State Health Officer Webcast, February 27, 2015 Wisconsin Division of Public Health Wisconsin Department of Health Services Thomas Haupt Influenza Surveillance.
Influenza Activity for FY 2014. IDAHO: Flu season is starting to wind down State Activity Code: Regional Vital Statistics: As of MMWR week 6, 12 influenza-

Influenza Activity for FY IDAHO: Flu season is starting to wind down State Activity Code: Regional Vital Statistics: As of MMWR week 6, 12 influenza-
Influenza Surveillance Update Health and Medical Subpanel Meeting July 13, 2010 Diane Woolard, VDH.

Influenza Surveillance Update Health and Medical Subpanel Meeting July 13, 2010 Diane Woolard, VDH.

Similar presentations

Ads by Google