1. Middle East Respiratory Syndrome (MERS) Ali ElRida ElMasri Aarushi Sharma

2. What is MERS? SARS-like Coronavirus family 24 th September 2012 6 th new type of coronavirus Tropism for non-ciliated bronchial ep.

3. Etiology Origin is debated England/Qatar/2012 1 or more zoonotic event? Mutation of existing virus? Unnoticed for 1 year Arabic peninsula

4. Transmission Person to person- low WHO says MERS-CoV “threat” Natural reservoir: Bats Antibodies in camels

5. Symptoms Fever Cough Shortness of breath Renal Failure Severe acute pneumonia Incubation period: 12 days

6. Statistics

8. Diagnosis and Prevention RT-PCR Vaccines are undergoing clinical trials Novavax, Greffex Standard Precautions

9. Treatment Acute Respiratory Support in hospital Drugs for other Coronavirus strains

10. References http://www.cdc.gov/coronavirus/mers/photos.html http://www.who.int/csr/disease/coronavirus_infections/IPCn CoVguidance_06May13.pdf http://www.who.int/csr/disease/coronavirus_infections/en/ http://www.theguardian.com/science/2013/may/13/new- coronavirus-mers-cov http://www.ncbi.nlm.nih.gov/pubmed/23782161 http://communities.washingtontimes.com/neighborhood/ste ps-authentic-happiness-positive- psychology/2013/may/30/coronavirus-severe-acute- respiratory-syndrome-dang/