2. What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

3. Help Chemical Reactions Occur Notice the enzyme is not used up in the reaction! Only a certain substrate will fit in the active site

4. How? Allows bonds in substrate to be broken more easily, with less input of energy

5. Another Example

6. Reaction Energy Diagrams Activation Energy

7. Input of energy required to break initial bonds and begin the reaction Even if reaction will release energy

8. Enzymes Lower Ea Make the transition state easier to reach

9. Endergonic vs. Exergonic

10. Specificity of Active Sites Enzymes only catalyze substrates with a complementary shape Any changes to the shape of the enzyme will disable the activity of the active site