1. Development of an Olfactory Stimulation Device for Brain Functional MRI Melanie Kotys and Martin Gilmore Advisor: Dr. David Pickens March 31, 1999

2. Background Functional MRI Olfactory Stimulation Device Prader-Willi Studies

3. Protocol rest smell 1 smell 2 rest smell 1 smell 2 Each rest and smell period for 20 seconds Total imaging time of 5:22

4. Problems with Current System Delayed delivery to subject Difficult operation Low scent delivery O2 1 2 3 15 L/min 15 mm ID plastic tubing head coil odors on gauze pad one way valves manual valves

5. First Design

6. Actuator Control switching of valve

7. Pneumatic valve Machining of valve Materials in valve

8. Scent Delivery Closer to subject Nasal Cannulae Helmet Velcro

9. Scent Filter Projection Slide Gauze filter Presoak filter

10. Future Endeavors Machining parts –Scent chambers –Valves Getting cannulae Building device Testing