Presentation is loading. Please wait.

Presentation is loading. Please wait.

Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty:

Published byShanon Lawson Modified over 9 years ago

Similar presentations

Presentation on theme: "Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty:"— Presentation transcript:

1 Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials by Giuseppe De Luca, Eliano Navarese, and Paolo Marino EHJ Volume 30(22):2705-2713 November 14, 2009 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

2 Flow diagram of the systematic overview process. Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

3 Glycoprotein IIb-IIIa inhibitors and mortality benefits at 30 day follow-up, with odds ratios and 95% confidence intervals (CI). Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

4 Funnel plot of all studies included in the meta-analysis. Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

5 (A) Weighted random-effects meta-regression analysis regressing the log odds ratio of mortality against the control group mortality rate expressed as odds using the inverse of the variance of the log odds ratio as weight; this graph shows a relationship between risk profile and mortality benefits from Gp IIb-IIIa inhibitors. Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

6 Glycoprotein IIb-IIIa inhibitors and benefits in re-infarction at 30 day follow-up, with odds ratios and 95% confidence intervals (CI). Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

7 (A) Weighted random-effects meta-regression analysis regressing the log odds ratio of re- infarction against the control group re-infarction rate expressed as odds using the inverse of the variance of the log odds ratio as weight; this graph shows no relationship between risk profile and benefits in re-infarction from Gp IIb-IIIa inhibitors. Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

8 Glycoprotein IIb-IIIa inhibitors and major bleeding complications at 30 day follow-up, with odds ratios and 95% confidence intervals (CI). Giuseppe De Luca et al. Eur Heart J 2009;30:2705-2713 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Download ppt "Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty:"

Similar presentations

A single dose of erythropoietin in ST-elevation myocardial infarction by Adriaan A. Voors, Anne M.S. Belonje, Felix Zijlstra, Hans L. Hillege, Stefan D.

A single dose of erythropoietin in ST-elevation myocardial infarction by Adriaan A. Voors, Anne M.S. Belonje, Felix Zijlstra, Hans L. Hillege, Stefan D.
Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies by Lawrence de Koning,

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies by Lawrence de Koning,
The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from APPROACH by Antigone.

The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from APPROACH by Antigone.
An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn.

An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn.
Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial by Atul Verma, Roberto Mantovan,

Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial by Atul Verma, Roberto Mantovan,
Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation by Jesper Hjortnaes, Jonathan.

Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation by Jesper Hjortnaes, Jonathan.
Endurance sport practice as a risk factor for atrial fibrillation and atrial flutter by Lluís Mont, Roberto Elosua, and Josep Brugada Europace Volume 11(1):11-17.

Endurance sport practice as a risk factor for atrial fibrillation and atrial flutter by Lluís Mont, Roberto Elosua, and Josep Brugada Europace Volume 11(1):11-17.
Clopidogrel pre-treatment in stable angina: for all patients >6 h before elective coronary angiography or only for angiographically selected patients a.

Clopidogrel pre-treatment in stable angina: for all patients >6 h before elective coronary angiography or only for angiographically selected patients a.
High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery disease by Sven Plein, Sebastian Kozerke,

High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery disease by Sven Plein, Sebastian Kozerke,
Guidelines for the diagnosis and treatment of non-ST- segment elevation acute coronary syndromes by Jean-Pierre Bassand, Christian W. Hamm, Diego Ardissino,

Guidelines for the diagnosis and treatment of non-ST- segment elevation acute coronary syndromes by Jean-Pierre Bassand, Christian W. Hamm, Diego Ardissino,
Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer.

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer.
Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment.

Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment.
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with.

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with.
Platelet thrombin receptor antagonism and atherothrombosis by Dominick J. Angiolillo, Davide Capodanno, and Shinya Goto EHJ Volume 31(1):17-28 January.

Platelet thrombin receptor antagonism and atherothrombosis by Dominick J. Angiolillo, Davide Capodanno, and Shinya Goto EHJ Volume 31(1):17-28 January.
Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay:

Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay:
MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue by.

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue by.
Interventions for prevention of post-operative atrial fibrillation and its complications after cardiac surgery: a meta-analysis by David C. Burgess, Michael.

Interventions for prevention of post-operative atrial fibrillation and its complications after cardiac surgery: a meta-analysis by David C. Burgess, Michael.
Awareness and perception of heart failure among European cardiologists, internists, geriatricians, and primary care physicians by Willem J. Remme, John.

Awareness and perception of heart failure among European cardiologists, internists, geriatricians, and primary care physicians by Willem J. Remme, John.
Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction by Mortimer Korf-Klingebiel,

Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction by Mortimer Korf-Klingebiel,
The combined influence of leisure-time physical activity and weekly alcohol intake on fatal ischaemic heart disease and all-cause mortality by Jane Østergaard.

The combined influence of leisure-time physical activity and weekly alcohol intake on fatal ischaemic heart disease and all-cause mortality by Jane Østergaard.

Similar presentations

Ads by Google