1. HAPPY THURSDAY Bellwork: Organize your Buff Binder, you have 5 minutes – then we will take a Buff Binder Quiz. On your Bellwork write “Organize Buff Binder”

2. Assignments Page 45 – DNA Candy Replication (Due Today) Page 46 – Comic Book Strip (Due Tomorrow) Most Missed Quiz: Cells/Molecule Transport (Friday) Notecard Definitions (Due Monday) Notecard ALL PARTS (Due Wednesday) Late Assignments Page 41 - Lab: Cornell Notes - DNA Model (-50%) Page 42 - DNA & Genes (-50%) Page 43 - Franklin, Watson, and Crick Article (-50%) Page 44 – Lab: DNA Extraction (-30%)

3. Unit 3.2 – Protein Synthesis Definitions Due Monday(10/26/15) All Parts Due Wednesday (10/28/15) 1.Uracil 2.Transcription 3.Translation 4.Central Dogma 5.Ribosome 6.Codon 7.Anticodon 8.Gene 9.Ribonucleic Acid (RNA) 10.Transfer RNA (tRNA) 11.Messenger RNA (mRNA) 12.Gene Expression Definitions list found on my website

4. Closure….Comic Book Replication Create a 6-strip comic book page describing the process of DNA Replication. Be creative in the representation of your setting and characters Include thought bubbles and character names (DNA, Helicase, DNA Polymerase, etc…) Must include a minimum of 5 colors Must include the following words DNA ReplicationHelicaseDNA PolymeraseSemiconservative Replication Replication ForkA, T, C, GAntiparallelWatson and Crick Will be due in the tray on Friday Small Group CHAMPS PG 46

5. Essential Question How is the information from DNA copied onto messenger RNA? Standard B.6C – Explain the purpose and process of transcription and translation using models of DNA and RNA PG 47

6. Let’s get some things straight… Replication- to make an exact copy Replication is like making a photocopy Transcription- to transfer from one recording form to another Transcription is like taking notes (same information, different form)

7. Well… 1.Copies are good to have as a backup—it’d be bad if something happened to DNA 2.You can just put down the part of the information you need—shorter/simpler Think of it like this: DNA = master copy RNA = blueprints…you don’t need the blueprints for the whole house to build the foundation

8. Central Dogma We’re only talking about the first part today DNARNAProtein Ribosome Translation Transcription Nucleus

9. Transcription (Big Ideas) Is the first step in making a protein (polypeptide) Occurs in the nucleus DNA is used to make RNA RNA is then sent out into the cell to make proteins It’s usually just a section of the DNA strand ( gene ) that codes for one specific protein

11. There are three main differences between DNA and RNA: 1) The sugar in RNA is ribose instead of deoxyribose. 2) RNA is single- stranded. 3) RNA contains uracil instead of thymine.

12. Comparing base pairing rules DNA to DNA C  G G  C T  A A  T DNA to RNA C  G G  C T  A A  U

13. Summarize the DNA to RNA base pairing rules in exactly 8 words.

14. Messenger RNA (mRNA) carries copies of instructions from DNA in the nucleus to the ribosome to make proteins. Transcription Animation Transcription Recap Transcription Animation Transcription Recap

15. Central Dogma Foldable 1.Fold the edges of your paper toward the BACK along the dotted lines. 2.Now fold the two sides in to meet in the middle (also marked with a dotted line). 3.Using the given ORIGINAL strand, complete the complementary strand. 4.Open your edges. Now “replicate” the DNA by filling in the two new strands. 5.Put your name on your paper and turn it in! I will keep them until next week, when we will add another step. PG 48

16. Save for a later date? What is DNA? - Video