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Advanced Glaucoma and Cataract: Management Options Regenbogen Michael – Ichilov Amer Radgonde – Hadassah Ron Yonina – Beilinson Reyvitch Svetlana – Barsilai Chetrit Noa – Assaf Harof Blumenfeld Oren - Wolfson Kaplan Audrey
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Definition Cataract: Visually significant Advanced glaucoma: Visual field loss Moderate-severe Inadequate lowering of target pressure
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Cataract Glaucoma Both are age –related Increased cataract PXF antiglaucomatous medications
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Prevalence of Visual Impairment in Older Americans
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Goals of Treatment Improve VA Reach target IOP Free from drugs Preserve VF
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Surgical options Glaucoma surgery Cataract surgery Combined surgery
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Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
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Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
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Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
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Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
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Surgical options Trabeculectomy Cataract surgery Combined surgery
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Stand alone Trabeculectomy Pros: Reduces IOP +++ phacotrabeculectomy or cataract extraction Caprioli J et al.Trans Am Ophthalmol Soc 1996. Cons: Cataractogeneous Higher complication rate (hypotony, significant chamber shallowing … ) AGIS investigators Arch Oph 2001
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Cataract extraction alone Pros: Cataract extraction decreases IOP per se (ACG>PXF>OAG) Dimitrov et al. Clin Exp Ophthal 2001 Friedman et al. Ophthalmology 2002 Cons: 10% IOP spike By 2 yr. 30% IOP worse than preoperative status Rainer et al. J Cat Ref Surg 1999 Hayashi et al. J Cat Ref Surg 2001
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Lens extraction in PAC Pre-Phaco/IOLPost-Phaco/IOL
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Combined Surgery: Best Choice One procedure improves VA and reduces IOP Quality of life Cataract surgery post trabeculectomy: more bleb failure
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Combined surgery : techniques ECCE / phaco ? One site vs. two sites Limbal or fornix based With/without MMC Phacotrabeculotomy 2 sites + MMC (Vass Curr Op. 2004)
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Complications Infections Hypotony Cataract formation Transient IOP elevation CME Choroidal effusion Suprachoroidal hemorrhage Leakage/failure of bleb Blebitis Endophthalmitis
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Cataract+ well controlled OAG Only cataract
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Cataract + CACG CATARACT SURGERY ONLY
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Cataract with uncontrolled OAG moderate damage Phacotrabeculectomy +/- MMC
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Cataract + advanced glaucoma (low target IOP) Phacotrabeculectomy+MMC trabeculectomy+MMC
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Thank You
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