2. Exploring Life Chapter 1 Advanced Placement Biology

3. Life Defies a simple, one-line definition. Defies a simple, one-line definition. Lends itself to mysticism. Lends itself to mysticism. Figure 1.1

4. What is biology?

5. Biology Bios = Greek for “life” Bios = Greek for “life” Logos = Greek for “study” or “thought” Logos = Greek for “study” or “thought” Biology - the study of living things Biology - the study of living things

6. Concept 1.1: Biologists explore life from the microscopic to the global scale. Concept 1.1: Biologists explore life from the microscopic to the global scale. The study of life: The study of life: Extends from the microscope scale of molecules and cells to the global scale of the entire living planet. Extends from the microscope scale of molecules and cells to the global scale of the entire living planet.

7. What does it mean to be alive? What characteristics define life? What are the criteria for something to be alive?

8. Figure 1.2 (c) Response to the environment (a) Order (d) Regulation (g) Reproduction (f) Growth and development (b) Evolutionary adaptation (e) Energy processing

9. What does it mean to be “living?” Some Characteristics: 1. Order- have a hierarchical organization (Fig 1.3).

10. A Hierarchy of Biological Organization The hierarchy of life The hierarchy of life Extends through many levels of biological organization Extends through many levels of biological organization

11. From the biosphere to organisms… From the biosphere to organisms… Figure 1.3 1 The biosphere 2. Ecosystems 3. Communities 4. Populations 5. Organisms 1.a. biome

12. From cells to atoms. From cells to atoms. Cell 8 Cells 6 Organs and organ systems 7 Tissues 10 Molecules 9 Organelles 50 µm 10 µm 1 µm Atoms Figure 1.3

13. Order Beyond the Organism Population- a group of individuals of same species occupying a given area at the same time. Population- a group of individuals of same species occupying a given area at the same time. Community- a number of interacting populations in a common environment. Community- a number of interacting populations in a common environment.

14. Order in Biology Ecosystem- organisms (biotic) interacting with their nonliving (abiotic) environment. Ecosystem- organisms (biotic) interacting with their nonliving (abiotic) environment. Biomes- major groupings of plants, animals, and microorganisms that occur over a wide geography and have distinct characteristics (ex. deserts, tropical rainforests) Biomes- major groupings of plants, animals, and microorganisms that occur over a wide geography and have distinct characteristics (ex. deserts, tropical rainforests)

15. The Emergent Properties of Systems Biological systems are much more than the sum of their parts. Biological systems are much more than the sum of their parts. Due to increasing complexity Due to increasing complexity New properties emerge with each step upward in the hierarchy of biological order New properties emerge with each step upward in the hierarchy of biological order

16. The Power and Limitations of Reductionism Reductionism- Reductionism- Involves reducing complex systems to simpler components that are more manageable to study.

17. The study of DNA structure, an example of reductionism The study of DNA structure, an example of reductionism Has led to further study of heredity, such as the Human Genome Project Has led to further study of heredity, such as the Human Genome Project Figure 1.9

18. A Closer Look at Ecosystems Each organism… Each organism… Interacts with its environment. Interacts with its environment. Both organism and environment… Both organism and environment… Are affected by the interactions between them. Are affected by the interactions between them.

19. Ecosystem Dynamics The dynamics of any ecosystem include two major processes The dynamics of any ecosystem include two major processes Cycling of nutrients, in which materials acquired by plants eventually return to the soil Cycling of nutrients, in which materials acquired by plants eventually return to the soil The flow of energy from sunlight to producers to consumers The flow of energy from sunlight to producers to consumers

20. Energy Conversion Activities of life… Activities of life… Require organisms to perform work, which depends on an energy source. Require organisms to perform work, which depends on an energy source. The exchange of energy between an organism and its surroundings involves the transformation from one form of energy to another. The exchange of energy between an organism and its surroundings involves the transformation from one form of energy to another.

21. Energy flows through an ecosystem Energy flows through an ecosystem Usually entering as sunlight and exiting as heat Usually entering as sunlight and exiting as heat Producers (plants and other photosynthetic organisms) Consumers (including animals) Sunlight Chemical energy Heat Ecosystem Figure 1.4

22. What does it mean to be “living?” 2. Responsiveness or Sensitivity- have a response to stimuli. Chemotactic Chemotactic Phototactic Phototactic Thigmotropic Thigmotropic Gravitropic Gravitropic

23. Is fire alive?

24. A Closer Look at Cells The cell The cell Is the lowest level of organization that can perform all activities required for life Is the lowest level of organization that can perform all activities required for life 25 µm Figure 1.5

25. The Cell’s Heritable Information Cells contain chromosomes made partly of DNA, the substance of genes Cells contain chromosomes made partly of DNA, the substance of genes Which program the cells’ production of proteins and transmit information from parents to offspring Which program the cells’ production of proteins and transmit information from parents to offspring Egg cell Sperm cell Nuclei containing DNA Fertilized egg with DNA from both parents Embyro’s cells with copies of inherited DNA Offspring with traits inherited from both parents Figure 1.6

26. The molecular structure of DNA The molecular structure of DNA Accounts for it information-rich nature. Accounts for it information-rich nature. DNA Cell Nucleotide A C T A T A C C G G T A T A (b) Single strand of DNA.. (a) DNA double helix. Figure 1.7 Nucleus

27. What does it mean to be “living?” 3. Growth, Development, and Reproduction- all use hereditary molecules to pass genetic information to offspring.

28. Two Main Forms of Cells All cells share certain characteristics All cells share certain characteristics They are all enclosed by a membrane They are all enclosed by a membrane They all use DNA as genetic information They all use DNA as genetic information There are two main forms of cells: There are two main forms of cells: Eukaryotic Eukaryotic Prokaryotic Prokaryotic

29. Prokaryotic cells Prokaryotic cells Lack the kinds of membrane-enclosed organelles found in eukaryotic cells. Lack the kinds of membrane-enclosed organelles found in eukaryotic cells. EUKARYOTIC CELL Membrane Cytoplasm Organelles Nucleus (contains DNA) 1 µm PROKARYOTIC CELL DNA (no nucleus) Membrane Figure 1.8

30. What does it mean to be “living?” 4. Regulation- have regulatory mechanisms to coordinate functions (transportation of nutrients, wastes, etc.); maintain homeostasis.

31. Feedback Regulation in Biological Systems A kind of supply-and-demand economy: A kind of supply-and-demand economy: Applies to some of the dynamics of biological systems. Applies to some of the dynamics of biological systems. The output, or product, of a process regulates that very process -feedback regulation. The output, or product, of a process regulates that very process -feedback regulation.

32. In negative feedback: In negative feedback: An accumulation of an end product slows the process that produces that product. An accumulation of an end product slows the process that produces that product. B A C D Enzyme 1 Enzyme 2 Enzyme 3 D D D D D D D D DD C B A Negative feedback Figure 1.11

33. In positive feedback: In positive feedback: The end product speeds up production. The end product speeds up production. WW X Y Z Z Z Z Z Z Z Z Z Z Z ZZ Z ZZ Z Z Z Y X Enzyme 4 Enzyme 5 Enzyme 6 Enzyme 4 Enzyme 5 Enzyme 6 Positive feedback Figure 1.12

34. Question: Are viruses alive?

35. Grouping Species: The Basic Idea Diversity is a hallmark of life. Diversity is a hallmark of life. Taxonomy: Taxonomy: is the branch of biology that names and classifies species according to a system of broader and broader groups is the branch of biology that names and classifies species according to a system of broader and broader groups

36. Classifying life Classifying life Species Genus Family Order Class Phylum Kingdom Domain Mammalia Ursus ameri- canus (American black bear) Ursus Ursidae Carnivora Chordata Animalia Eukarya Figure 1.14

37. The Three Domains of Life At the highest level, life is classified into three domains: At the highest level, life is classified into three domains: Bacteria Bacteria Archaea Archaea Eukarya Eukarya Domain Bacteria and domain Archaea Domain Bacteria and domain Archaea Consist of prokaryotes Consist of prokaryotes Domain Eukarya, the eukaryotes Domain Eukarya, the eukaryotes Includes the various protist kingdoms and the kingdoms Plantae, Fungi, and Animalia Includes the various protist kingdoms and the kingdoms Plantae, Fungi, and Animalia

38. Life’s three domains Life’s three domains Figure 1.15 100 µm 0.5 µm 4 µm Bacteria are the most diverse and widespread prokaryotes and are now divided among multiple kingdoms. Each of the rod-shaped structures in this photo is a bacterial cell. Protists (multiple kingdoms) are unicellular eukaryotes and their relatively simple multicellular relatives.Pictured here is an assortment of protists inhabiting pond water. Scientists are currently debating how to split the protists into several kingdoms that better represent evolution and diversity. Kingdom Plantae consists of multicellula eukaryotes that carry out photosynthesis, the conversion of light energy to food. Many of the prokaryotes known as archaea live in Earth‘s extreme environments, such as salty lakes and boiling hot springs. Domain Archaea includes multiple kingdoms. The photo shows a colony composed of many cells. Kindom Fungi is defined in part by the nutritional mode of its members, such as this mushroom, which absorb nutrientsafter decomposing organic material. Kindom Animalia consists of multicellular eukaryotes that ingest other organisms. DOMAIN ARCHAEA

39. Unity in the Diversity of Life As diverse as life is As diverse as life is There is also evidence of remarkable unity There is also evidence of remarkable unity Cilia of Paramecium. The cilia of Paramecium propel the cell through pond water. Cross section of cilium, as viewed with an electron microscope 15 µm 1.0 µm 5 µm Cilia of windpipe cells. The cells that line the human windpipe are equipped with cilia that help keep the lungs clean by moving a film of debris-trapping mucus upward. Figure 1.16

40. Concept 1.4: Evolution accounts for life’s unity and diversity Concept 1.4: Evolution accounts for life’s unity and diversity The history of life The history of life Is a saga of a changing Earth billions of years old Is a saga of a changing Earth billions of years old Figure 1.17

41. The evolutionary view of life… The evolutionary view of life… Came into sharp focus in 1859 when Charles Darwin published On the Origin of Species by Natural Selection Came into sharp focus in 1859 when Charles Darwin published On the Origin of Species by Natural Selection Figure 1.18

42. The Origin of Species articulated two main points… The Origin of Species articulated two main points… Descent with modification Descent with modification Natural selection Natural selection Figure 1.19

43. Natural Selection Darwin proposed natural selection Darwin proposed natural selection As the mechanism for evolutionary adaptation of populations to their environments As the mechanism for evolutionary adaptation of populations to their environments Population of organisms Hereditary variations Differences in reproductive success Evolution of adaptations in the population Overproduction and struggle for existence Figure 1.20

44. Natural selection is the evolutionary process that occurs… Natural selection is the evolutionary process that occurs… When a population’s heritable variations are exposed to environmental factors that favor the reproductive success of some individuals over others. When a population’s heritable variations are exposed to environmental factors that favor the reproductive success of some individuals over others. 1 Populations with varied inherited traits 2 Elimination of individuals with certain traits. 3 Reproduction of survivors. 4 Increasing frequency of traits that enhance survival and reproductive success. Figure 1.21

45. Darwin, 1835, Galapagos

47. Darwin’s Evidence of Evolution Fossil Record (Glyptodont -- >armadillo) Fossil Record (Glyptodont -- >armadillo) Geographical Distribution (similar climates have unrelated plants and animals; climate not causing diversity) Geographical Distribution (similar climates have unrelated plants and animals; climate not causing diversity) Oceanic Islands (Galapagos finches and Cape Verde Island birds are not similar) Oceanic Islands (Galapagos finches and Cape Verde Island birds are not similar)

48. Darwin’s Finches

49. The Galapagos Archipelago

50. Bartoloma Island

51. Isabela Island

52. Darwin proposed that natural selection Darwin proposed that natural selection Could enable an ancestral species to “split” into two or more descendant species, resulting in a “tree of life” Could enable an ancestral species to “split” into two or more descendant species, resulting in a “tree of life” Large ground finch Small ground finch Geospiza magnirostris Seed eater Sharp-beaked ground finch Camarhynchus psitacula Green warbler finch Large tree finch Large cactus ground finch Ground finches Tree finches Insect eaters Bud eater Warbler finches Common ancestor from South American mainland Gray warbler finch Certhidea olivacea Certhidea fusca Geospiza difficilis Cactus flower eater Geospiza scandens Seed eater Geospiza conirostris Geospiza fortis Medium ground finch Geospiza fuliginosa Mangrove finch Cactospiza heliobates Cactospiza pallida Woodpecker finch Medium tree finch Camarhynchus pauper Small tree finch Vegetarian finch Camarhynchus parvulus Platyspiza crassirostris Cactus ground finch Figure 1.23

53. Large ground finch Small ground finch Geospiza magnirostris Seed eater Sharp-beaked ground finch Camarhynchus psitacula Green warbler finch Large tree finch Large cactus ground finch Ground finches Tree finches Insect eaters Bud eater Warbler finches Common ancestor from South American mainland Gray warbler finch Certhidea olivacea Certhidea fusca Geospiza difficilis Cactus flower eater Geospiza scandens Seed eater Geospiza conirostris Geospiza fortis Medium ground finch Geospiza fuliginosa Mangrove finch Cactospiza heliobates Cactospiza pallida Woodpecker finch Medium tree finch Camarhynchus pauper Small tree finch Vegetarian finch Camarhynchus parvulus Platyspiza crassirostris Cactus ground finch Figure 1.23

54. New Evidence that Darwin Did Not Have Age of the Earth- 4.5 billion year old. Better dating techniques than in Darwin’s time. Age of the Earth- 4.5 billion year old. Better dating techniques than in Darwin’s time. Fossil Record- beginning of life- 3.5 billion; transitional forms found. Ex. Archaeopteryx, feathered (150 million years ago). Fossil Record- beginning of life- 3.5 billion; transitional forms found. Ex. Archaeopteryx, feathered (150 million years ago).

55. Archaeopteryx

56. Archaeopteryx

57. Transitional Examples? Rodhocetus balochistanensis Modern Whales

58. A Walking Whale? Ambulocetus natans

59. Vestigial Structures Existing structures that have no apparent function, but resemble structures of presumed ancestors. Existing structures that have no apparent function, but resemble structures of presumed ancestors. Examples: human appendix; muscle set in humans for moving ears; Examples: human appendix; muscle set in humans for moving ears;

60. New Evidence that Darwin Did Not Have Mechanism of Heredity- traits through DNA. Mechanism of Heredity- traits through DNA. Comparative Anatomy (Fig. 1.14) Homologous vs. Analogous Structures. Comparative Anatomy (Fig. 1.14) Homologous vs. Analogous Structures.

61. The products of natural selection The products of natural selection Are often exquisite adaptations of organisms to the special circumstances of their way of life and their environment Are often exquisite adaptations of organisms to the special circumstances of their way of life and their environment Figure 1.22

62. The Tree of Life Many related organisms Many related organisms Have very similar anatomical features, adapted for their specific ways of life. Have very similar anatomical features, adapted for their specific ways of life. Such examples of kinship Such examples of kinship Connect life’s “unity in diversity” to Darwin’s concept of “descent with modification.” Connect life’s “unity in diversity” to Darwin’s concept of “descent with modification.”

63. Show me an example of homologous structures! Compare a human hand and bat wing.

64. Natural Selection Natural Selection- conditions in an environment that favor certain traits of an organism; these traits become more common in succeeding generations; must be inheritable; population gradually changes. Natural Selection- conditions in an environment that favor certain traits of an organism; these traits become more common in succeeding generations; must be inheritable; population gradually changes.

65. Darwin’s Theory of Evolution Natural selection is the driving force of changes within species populations. Natural selection is the driving force of changes within species populations.

66. Concept 1.5: Biologists use various forms of inquiry to explore life At the heart of science is inquiry At the heart of science is inquiry A search for information and explanation, often focusing on specific questions A search for information and explanation, often focusing on specific questions Biology blends two main processes of scientific inquiry Biology blends two main processes of scientific inquiry Discovery science Discovery science Hypothesis-based science Hypothesis-based science

67. Discovery Science Discovery Science: Discovery Science: Describes natural structures and processes as accurately as possible through careful observation and analysis of data. Describes natural structures and processes as accurately as possible through careful observation and analysis of data.

68. Types of Data Data: Data: Are recorded observations. Are recorded observations. Can be quantitative or qualitative. Can be quantitative or qualitative. Figure 1.24

69. Induction in Discovery Science In inductive reasoning: In inductive reasoning: Scientists derive generalizations based on a large number of specific observations. Scientists derive generalizations based on a large number of specific observations.

70. Hypothesis-Based Science In science, inquiry that asks specific questions: In science, inquiry that asks specific questions: Usually involves the proposing and testing of hypothetical explanations, or hypotheses. Usually involves the proposing and testing of hypothetical explanations, or hypotheses.

71. Deduction: The “If…then” Logic of Hypothesis-Based Science In deductive reasoning: In deductive reasoning: The logic flows from the general to the specific. The logic flows from the general to the specific. If a hypothesis is correct: If a hypothesis is correct: Then we can expect a particular outcome. Then we can expect a particular outcome.

72. Inductive vs. Deductive Reasoning Deductive- general principles are tested and used to examine specific cases. Ex. Math and Philosophy Deductive- general principles are tested and used to examine specific cases. Ex. Math and Philosophy Inductive- use specific observations to construct general principles. Ex. Science Inductive- use specific observations to construct general principles. Ex. Science

73. A Biological Example of a Theory How can living things change over time?

74. Why do male and female lions look different?

75. Concept 1.6: A set of themes connects the concepts of biology Concept 1.6: A set of themes connects the concepts of biology Underlying themes Provide a framework for understanding biology Provide a framework for understanding biology

76. Eleven themes that unify biology Table 1.1

77. Common Themes in Biology Science as a Process Science as a Process Evolution Evolution Energy Transfer Energy Transfer Continuity and Change Continuity and Change Relationship of Structure and Function Relationship of Structure and Function Regulation Regulation Interdependence in Nature Interdependence in Nature Science, Technology, and Society Science, Technology, and Society

78. How many moths do you see?