Download presentation
Presentation is loading. Please wait.
Published byBertina Merritt Modified over 8 years ago
1
Therapies For T1D Insulin therapy Transplantation Islet Encapsulation
8
Subcutaneous
15
Islet Transplantation
18
600 500 400 300 200 100 2 4 6 810 122 46 810 600 500 400 300 200 100 0 12 a.m.p.m. Post-transplant Pre-transplant Time of day Blood glucose (mg/dl) Shapiro et al. N Engl J Med 2000; 343:230-238
24
Islet Encapsulation
25
Aileen King Structure of an Alginate Microcapsule
26
Aileen King Production of alginate/poly-L-lysine/alginate capsules
27
Aileen King Cells attached to the surface of capsules (A) and fibre production by cells on the capsule (B).
28
Igor Lacik
30
Long-Term Graft Function of Adult Rat and Human Islets Encapsulated in Novel Alginate- Based Microcapsules After Transplantation in Immunocompetent Diabetic Mice S Schneider, P. Feilen, F Brunnenmeier, T Minnemann, H Zimmermann, U Zimmermann, and M M. Weber Diabetes 54:687–693, 2005
31
Nonencapsulated and encapsulated adult rat islets
32
Nonencapsulated and encapsulated adult human islets
Similar presentations
© 2024 SlidePlayer.com. Inc.
All rights reserved.