1. Catalyst 1.What structure in the cell is made up of condensed chromatin? 2.During what stage of interphase is DNA duplicated? 3.What are the two things found inside the nucleus? 4.When we are talking about mitosis, what kind of cells are we talking about?

2. Mitosis and the Cell Cycle Ms. Klinkhachorn February 17, 2010

3. Interphase Longest phase of the cell cycle – 90% of a cell’s life spent here Has 3 stages: – G1 – S – G2

4. Mitotic Phase Occurs after interphase Mitosis has 4 stages: – Prophase – Metaphase – Anaphase – Telophase Cytokinesis

6. Interphase

9. Prophase

10. Nucleus starts to break down Nucleolus disappears Chromosomes formed from chromatin Spindles start to grow and separate

13. Metaphase

14. Spindles located at opposite ends of the cell – Spindle fully grown Chromosomes line up across the middle of the cell Spindle fibers (microtubules) attach to chromosomes at the centromere

17. Anaphase

18. Microtubules attached to chromosomes shrink – Causes the sister chromatids to separate Microtubules not attached to chromosomes get longer – Causes the cell to stretch apart more

21. Telophase and Cytokinesis

22. Telophase – Nucleus and nucleolus reform – Chromosomes fall apart (into chromatin strands) – Spindle disappears Cytokinesis – This is NOT a part of mitosis, but starts during telophase – Division of the cytoplasm Cells pinch inwards to form two daughter cells

25. End Results of Mitosis – Daughter Cells

27. Exit Slip 1.List the phases of mitosis in order. 2.What is cytokinesis? 3.Name the phase when.. The nucleus reappears The chromosomes move to opposite ends of the cells The nucleolus disappears The spindle fibers shorten and lengthen for movement The chromosomes line up in the middle of the cell

28. Mitosis animations http://www.cellsalive.com/mitosis.htm http://highered.mcgraw- hill.com/sites/0073031216/student_view0/ex ercise13/mitosis_movie.html http://highered.mcgraw- hill.com/sites/0073031216/student_view0/ex ercise13/mitosis_movie.html http://highered.mcgraw- hill.com/sites/0072437316/student_view0/ch apter11/animations.html#