1. Dr Nikunj Bhatt

7. First line Defense:  Epidermis  Mucus Membranes  Mucus  Hairs  Cilia  Lacrimal appartus  lysosome  Saliva  Flow of Urine  Vagina Secretion  Defecation  Vomiting  Sebum  Perspiration  Gastric Juice Dr Nikunj Bhatt

8. Second line Defense:  Antimicrobial Protein  In Blood and Interstitial fluids  WBCs secretes Interferon  Stops replication  They are α, β,Y types Compliment System  promotes Phagocytosis Transferrin  Reduce Iron to inhibit growth of bacteria Dr Nikunj Bhatt

9. Natural Killer cells and phagocytosis:  5-10 % are NK [natural Killer] next to first line and Antimicrobial protein  Neutrophils and Macrophages: are two major Phagocytes has five phases  Chemotaxis  Adherence  Ingestion  Digestion  Killing Dr Nikunj Bhatt

10.  Inflammation:  Tissue damage  Redness,pain,heat and swelling Dr Nikunj Bhatt

11.  Maturation of t cells Dr Nikunj Bhatt

12.  Maturation of B cells Dr Nikunj Bhatt

13.  Antigen  Immunogenicity  Reactivity  Receptors  epitope Dr Nikunj Bhatt

14.  APCs [Antigen Presenting Cells] Dr Nikunj Bhatt

15.  Activation Proliferation and Differentiation of T cells Dr Nikunj Bhatt

16.  Activation Proliferation and Differentiation of B cells Dr Nikunj Bhatt