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Aravind Eye Hospital, Madurai
Serpiginous choroiditis/Geographic helicoid peripapillary choroidopathy (GHPC) Dr. Rathinam Sivakumar HOD - Uveitis Services Aravind Eye Hospital, Madurai India
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Ocular History 19 year old male, engineering student presented with c/o sudden onset painless progressive defect of vision in OD since 5 days no similar complains in the past
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General History No h/o trauma
No h/o cough, fever, weight loss in recent past No h/o urogenital ulcerations No h/o bleeding discariasis No h/o neurological symptoms No h/o any systemic illness
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General examination patient moderately built and fairly nourished
conscious, co-operative, oriented to time, place and person afebrile no joint swellings no rashes, nodules, vesicles no pallor, icterus, cyanosis or lymphadenopathy BP-110/80 mm Hg pulse -80 /min, regular, good volume, equal on both sides
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General Examination CVS - Normal RS - Normal Abdomen – Normal
CNS – No focal neurological deficit Visual Acuity (Snellen’s) OD-6/60 OS-6/6
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Ocular Examination Ocular Examination – OD OS Lids Normal Conjunctiva
Cornea Clear Anterior Chamber Normal Depth Iris Normal Colour and Pattern Pupil Normal size and reacting to light Lens Ocular Movements Full Ocular Examination –
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Fundus OD: Yellow arrow- healed lesions
Red arrow-active lesion over macula OS: healed chorioretinal scars
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FFA FFA- Active stage “Block early, stain late” Distinctly insidious
Chronic Recurrent variable in size and shape, variable stages of progression, Serpiginous choroiditis
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Investigations TLC - 9,600 cells/cumm DLC – N 58%/ L 30%/ E 12 %
RBC million cells/cumm Hb – 13.4 gm% ESR 4mm-30min, 10 mm in 1 hr Fasting sugar - 73 mg % Blood urea - 14 mg% Serum creatinine mg% Tuberculin skin test (5 ppd) - negative TPHA – negative HIV - negative
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Diagnosis Serpiginious chorioretinitis
not associated to systemic disorders
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Diagnosis based on Clinical picture FFA findings Investigations
Negative tuberculin skin test Negative VDRL Normal spiral CT chest
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Treatment Oral prednisolone 60mg OD in tapering doses
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Follow ups of the OS June 27, 2009 6/60 2 weks later 6/36
3 weeks later /24 no recurrences
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Thank you Asymptomatic if macula is spared Symptoms GHPC
chronic recurrent Often we see a previous scar Early hypo and leak late Asymptomatic if macula is spared Central hypo and leaking borders Vision loss > 2 lines GHPC Symptoms Onset course FFA Active stage FFA Healed stage prognosis Thank you
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