1. Overview of Pesticides and Toxics Research Programs: Safe Pesticides/Safe Products and Endocrine Disruptors Elaine Z. Francis, Ph.D. National Program Director, Pesticides & Toxics Research Program ORD Managers’ Workshop March 6, 2007

2. SP2 Multi-Year Plan (2007-2015) Long-Term Goals LTG 1 - 1) prioritization of testing requirements, 2) enhanced interpretation of data to improve their human health and ecological risk assessments, and 3) decisionmaking regarding specific individual or classes of pesticides and toxic substances that are of high priority. LTG 2 -- probabilistic risk assessments to protect natural populations of birds, fish, other wildlife, and non-target plants. LTG 3 -- decisionmaking related to products of biotechnology. OPPTS and/or other organizations use the results of ORD’s research as scientific foundation for:

3. Status MYP was updated December 2006 External review by SP2 Subcommittee of Board of Scientific Counselors - February 7-9, 2007 Submission of PART to OMB - March 2007 Website - by end of 2007

4. EDCs Multi-Year Plan (2007-2015): Long-Term Goals LTG 1 - Provide a better understanding of the science underlying the effects, exposure, assessment, and management of endocrine disruptors LTG 2 - Determine the extent of the impact of endocrine disruptors on humans, wildlife, and the environment LTG 3 - Support EPA’s screening and testing program

5. Status Updating Multi-Year Plan – by August 2007 Mid-Cycle review by EDCs Subcommittee of Board of Scientific Counselors – September 2007 Held interagency workshop – February 20-22, 2007; another one organized for August 2007 Synthesis document on three research areas by end of 2007 Website by the end of 2007

6. Future Priorities: SP2 and EDCs Develop websites to communicate results Improve coordination/leveraging with other research programs Identify/finalize synthesis documents Improve involvement of Regional input Improve engagement with OPPTS (and OW) senior management Continue to develop cross-lab/center opportunities for integrated research Continue to hold targeted scientist to scientist workshops Visit labs/regions