1. | kvi - center for advanced radiation technology 1 KVI-Center for Advanced Radiation Technology M.A. Hofstee 19-sep-2014 RADSAFE Kick-off, CERN

2. | kvi - center for advanced radiation technology Research Activities ›Proton Therapy and Medical Instrumentation development ›Charge Particle Irradiations (10 + years) to Medical Therapy Standards ›Accelerator and Ion Sources ›In-house technical services (CART) 2 PET scan 1988 with UMCG Emittance meter (PANTECHNIK) Proton dosimetry Proton Radiography

3. | kvi - center for advanced radiation technology AGOR-FIRM Facility for Irradiation of Materials ›Flexible In Air Set-up ›protons to Xenon  P: 40 MeV to 190 MeV  HI: 30 MeV/u cocktail ›Flat fields (± 3%) ›Large fields  P: up to 14 cm ø  HI: up to 3.5 cm ø ›Low to High Flux  P up to 10 9 p/(cm 2 s)  HI up to 10 5 p/(cm 2 s) ›Customizable Degrader 3 http://www.agorfirm.nl

4. | kvi - center for advanced radiation technology Potential Projects ›WP3.2: Comparative study of Higher Energy Beams with 10 MeV/u. Adjustment of Heavy Ion Protocols. ›WP1.1: Benchmarking Laser versus Heavy Ion Irradiation. ›WP3.1: Radiation hardness of complete systems used in proton-therapy environment, including integrated electronics, scintillation crystals and photosensors. ›WP1-3: Providing Beam Time (at cost) 4