1. Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Active Lecture Questions for use with Classroom Response Systems Biology, Seventh Edition Neil Campbell and Jane Reece Edited by William Wischusen, Louisiana State University Chapter 12 The Cell Cycle

2. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings Using the data in the table below, the best conclusion concerning the difference between the cell types is: a)beta and gamma contain the same amount of DNA. b)beta contains more RNA than gamma. c)gamma contains 48 times more DNA and RNA than beta. d)beta has less DNA than gamma, but more than delta e)Delta cells can be found in quickly regenerating tissues Cell TypeG1G1 SG2G2 M Beta18241216 Delta100000 Gamma18481420 Minutes Spent in Cell Cycle Phases

3. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings Cytokinesis usually, but not always, follows mitosis. If a cell completed mitosis but not cytokinesis, what would be the result? a)a cell with a single large nucleus b)a cell with high concentrations of actin and myosin c)a cell with two abnormally small nuclei d)a cell with two nuclei e)a cell with two nuclei but with half the amount of DNA

4. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings The decline of MPF activity at the end of mitosis is caused by: a.The destruction of the protein kinase (Cdk) b.Decreased synthesis of cyclin c.The degradation of cyclin d.Synthesis of DNA e.An increase in the cell’s volume-to-genome ratio

5. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle was the nucleus with 6 picograms of DNA? a)G 0 b)G 1 c)S d)G 2 e)M

6. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. Those cells would have __________ picograms at the end of the S phase and __________ picograms at the end of G 2. a)8... 8 b)8... 16 c)16... 8 d)16... 16 e)12... 16

7. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings A particular cell has half as much DNA as some of the other cells in a mitotically active tissue. The cell in question is most likely in a)G 1. b)G 2. c)prophase. d)metaphase. e)anaphase.

8. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings A cell in which of the following phases would have the least amount of DNA? a)G 0 b)G 2 c)prophase d)metaphase e)anaphase

9. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings Which of the following statements about mitosis is not true? a.Mitosis occurs after DNA replication b.Mitosis is followed by cytokinesis, producing 2 genetically identical daughter cells c.Mitosis plays a role in growth, repair, and asexual reproduction d.In mitosis, only half of one’s genome is passed from the parent cell to daughter cells e.Mitosis is a continuous process with observable structural features. The general order of the processes are replication, alignment, and separation of chromosomes.

10. Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings

11. 10.The rhythmic changes in cyclin concentration in a cell cycle are due to a)its increased production once the restriction point is passed. b)the cascade of increased production once its enzyme is phosphorylated by MPF. c)its degradation, which is initiated by active MPF. d)the correlation of its production with the production of Cdk. e)the binding of the growth factor PDGF.