1. SHINE: S eattle’s H ub for I ndustry-driven N anotechnology E ducation North Seattle College Nanoparticle Synthesis and Applications Train the NanoTeacher Workshop July 16, 2014

2. Silver Nanoparticles Range of yellowish colors depending on size ◦ Used to make yellow stained glass Antimicrobial ◦ Break down the cell membrane destroying the cell SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 2

3. Ag Citrate Ag Citrate Ag Na + SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 3

4. Silver Nanoparticle Products SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 4

5. Ethics Are silver nanoparticles safe? Direct contact with open wounds Improved healing for burn victims Blood brain barrier What are safe levels? SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 5

6. Color of Gold SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 6

7. Salt Sensors Utilize optical properties of gold nanoparticles Salt present = color change SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 7

8. Before Adding Salt Salt Added SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 8

9. Other Gold Nanoparticle Uses Home pregnancy tests DNA or antibody sensors Drug delivery Diagnostics Stained glass SHINE: Seattle’s Hub for Industry-driven Nanotechnology Education 9 Colon cancer detected with the help of gold nanoparticles Source: MIZZOU magazine

10. References http://www.topnews.in/health/your-non-stinky-sock-might-be-killing-environment-21882http://www.topnews.in/health/your-non-stinky-sock-might-be-killing-environment-21882 - socks Your Non-stinky Sock Might Be Killing the Environment | TopNews. Photograph. TopNews. 10 Apr. 2008. Web. 10 Aug. 2010.. http://www.scientificamerican.com/article.cfm?id=silver-coating-fights-microbeshttp://www.scientificamerican.com/article.cfm?id=silver-coating-fights-microbes – paint A Silver Coating in the Fight Against Microbe. Photograph. Science News, Articles and Information | Scientific American. By Monica Heger. 2 May 2008. Web. 10 Aug. 2010.. http://www.beyondpesticides.org/antibacterial/health/nano.htmhttp://www.beyondpesticides.org/antibacterial/health/nano.htm - pacifier Nanosilver: Health Effects. Photograph. Beyond Pesticides. Web. 10 Aug. 2010.. http://www.colloidal-silver.com.au/http://www.colloidal-silver.com.au/ - bandaid Silver Strip. Photograph. Colloidal Silver Australia for All Silver Generators and Products. Web. 10 Aug. 2010.. http://mizzoumag.missouri.edu/2012/11/gold-nanorods-diagnose-colon-cancer/http://mizzoumag.missouri.edu/2012/11/gold-nanorods-diagnose-colon-cancer/ - colon cancer cells Gold Nanorods Diagnose Colon Cancer: Nanoparticles tagged with peptides fit like keys into tumor receptors.. Web. 11 July 2013.. This material is based upon work supported by the National Science Foundation under Grant Number 1204279. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. 10