1. Unit 5-5 Notes Mr. Hefti – Pulaski Biology

3. Type of cellFunctionLocation MacrophageIngests pathogensSpleen, lungs, blood NeutrophilEngulfs / destroys pathogensBloodstream Natural killer cell Punctures infected cellsInfected cells Helper T cellActivates B cells and Cytotoxic T cells Bloodstream Cytotoxic T cell Punctures infected cellsInfection sites B cellForms plasma cellsInfection sites Plasma cellReleases antibodiesBloodstream Memory cellProtects against defeated pathogens Bloodstream

4. 1. Antigen triggers IR 2. Macrophage “swallows” pathogen 3. Helper T and B cells activated 4. Antibodies bind to antigen marking cell for destruction 5. Cytotoxic T destroys marked cells

5. Refer to Tiger p. 936 to label! Virus Viral antigen Macrophage Viral antigen Helper T cell Receptor proteins Cytotoxic T cell B cell Plasma cell Infected body cells Antibodies Viruses Viral antigen Receptor protein Antibody

6.  Immune system exposed to weakened or harmless version of pathogen  Antibody production stimulated prior to actual exposure  BBC video clip BBC video clip

8. Type of cellFunctionLocation MacrophageSpleen, lungs, blood NeutrophilEngulfs / destroys pathogens Punctures infected cellsInfected cells Helper T cellActivates B cells and Cytotoxic T cells Bloodstream Punctures infected cellsInfection sites B cellForms plasma cells Plasma cell Protects against defeated pathogens Bloodstream Type of cellFunctionLocation MacrophageSpleen, lungs, blood NeutrophilEngulfs / destroys pathogens Punctures infected cellsInfected cells Helper T cellActivates B cells and Cytotoxic T cells Bloodstream Punctures infected cellsInfection sites B cellForms plasma cells Plasma cell Protects against defeated pathogens Bloodstream Type of cellFunctionLocation MacrophageSpleen, lungs, blood NeutrophilEngulfs / destroys pathogens Punctures infected cellsInfected cells Helper T cellActivates B cells and Cytotoxic T cells Bloodstream Punctures infected cellsInfection sites B cellForms plasma cells Plasma cell Protects against defeated pathogens Bloodstream Type of cellFunctionLocation MacrophageSpleen, lungs, blood NeutrophilEngulfs / destroys pathogens Punctures infected cellsInfected cells Helper T cellActivates B cells and Cytotoxic T cells Bloodstream Punctures infected cellsInfection sites B cellForms plasma cells Plasma cell Protects against defeated pathogens Bloodstream