1. Respiration Details PPT

2. Sunlight provides the energy that eventually becomes ATP in you!

3. Photosynthesis Respiration Inputs Outputs C6H12O6 + O2 CO2 + H2O + ATP
Light CO2 + H2O C6H12O6 + O2
Inputs
Outputs
C6H12O6 + O2
CO2 + H2O ATP
Respiration

4. Cellular Respiration

5. What’s ATP used for?

6. Glycolysis – In the cytosol
Start with Glucose
Uses 2 ATP’s
Makes 4 ATP’s
Makes 2 NADH’s
Left with 2 pyruvates

7. Glycolysis - in the cytosol
NOTICE THE SPLITTING HERE!
EVERYTHING FOLLOWNG MUST BE MULTIPLIED BY 2!

8. Pyruvate to the mitochondria: “Link Step”

9. Kreb’s Cycle – in the mitochondrial matrix

10. Electron Transport Chain (detailed)
Electron Transport Chain – virtual animation
ATP synthase in mitochondria – virtual animation

11. End of notes
Friday 11-13

12. Where do the electrons come from?

13. ATP synthase allows for chemiosmosis

14. Reactions in Respiration
Inputs
Outputs
Glycolysis (cytoplasm)
Glucose
2ATP
4ADP
2NAD+
Krebs Cycle (mitochondria)
Pyruvate
NAD+
CoA
FAD
ADP
Glycolysis (Cytoplasm)
2ADP
4ATP
2NADH
2 pyruvate
Krebs Cycle (mitochondria)
NADH
CO2
FADH2
ATP

15. Reactions in Respiration (cont.)
Inputs
Outputs
Electron Transport Chain in mitochondria membrane
NADH
FADH2 O2
Electron Transport Chain in mitochondria membrane
NAD+
FAD
ATP
H2O

16. Cellular Respiration Summary
C6H12O6 + O2
CO2 + H2O ATP
3 Basic Steps:
Glycolysis (in the cytoplasm)
Kreb’s Cycle (inner mitochondrial space)
Electron Transport Chain (mitochondrial membrane)
glucose
pyruvate + ATP + NADH
pyruvate
NADH + FADH2 + ATP + CO2
NADH + FADH2 + O2
ATP + H20

17. Review – Big Picture

18. Control of Respiration … feedback systems
Lots of AMP (low energy molecule)
Stimulates enzyme to produce ATP
Lots of ATP or Citrate
Shuts down enzyme to prevent overproduction

19. No oxygen = anaerobic pathway
Yeast/bacteria
Produce ethanol when deprived of oxygen … still has some energy
Humans
Produce lactic acid when deprived of oxygen
Recycled in liver to produce pyruvate

20. Anaerobic Respiration
Without Oxygen
No electron transport chain … less ATP
2 types:
Alcoholic fermentation: (bacteria, yeast)
Pyruvate + NADH Ethanol + NAD+ + CO2
Lactic Acid fermentation: (animals like you)
Pyruvate + NADH Lactic Acid + NAD+ What’s different about these two equations?
How can you set up an experiment to detect the difference?