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This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC,

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Presentation on theme: "This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC,"— Presentation transcript:

1 This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/10.1682/JRRD.2012.08.0147 Slideshow Project DOI:10.1682/JRRD.2012.08.0147JSP Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion Natalia C. Rodrigues, PhD; Lívia Assis, PhD; Kelly R. Fernandes, MSc; Angela Magri; Daniel A. Ribeiro, PhD; Roberta Brunelli, MSc; Daniela C. C. Abreu, PhD; Ana Claudia M. Renno, PhD

2 This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/10.1682/JRRD.2012.08.0147 Slideshow Project DOI:10.1682/JRRD.2012.08.0147JSP Aim – Evaluate effects of 660 nm low-level laser therapy (LLLT) on muscle regeneration after cryolesion in rat tibiales anterior (TA). Relevance – Studies have shown that laser irradiation favors regeneration of skeletal muscle, shortening inflammatory phase and accelerating proliferative and maturation phases of skeletal muscle regeneration.

3 This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/10.1682/JRRD.2012.08.0147 Slideshow Project DOI:10.1682/JRRD.2012.08.0147JSP Method 63 Wistar rats divided into: – Control group (CG). – 10 J/cm2 laser-treated group (G10). – 50 J/cm2 laser treated group (G50). Compared 10 and 50 J/cm 2 fluences 7, 14, and 21 d after cryolesion on TA through morphology and muscle tissue structure analysis. Inflammatory process, granulation tissue, tissue structure, number of blood vessels, and immunomarkers were evaluated histologically and by immunohistochemistry analysis.

4 This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/10.1682/JRRD.2012.08.0147 Slideshow Project DOI:10.1682/JRRD.2012.08.0147JSP Results Main finding: – Both laser-treated groups presented better histological pattern. Earlier recruitment of cell infiltrate Higher amount of newly formed muscle fiber. More organized muscle tissue structure at the lesion.

5 This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/10.1682/JRRD.2012.08.0147 Slideshow Project DOI:10.1682/JRRD.2012.08.0147JSP Conclusion Results suggest that LLLT, at both fluences, positively affects injured skeletal muscle in rats, accelerating muscle-regeneration process.

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