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Figure 10.6 Levels of Functional Organization in Skeletal Muscle Fiber
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Figure 10.7 Thick and Thin Filaments
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Sliding filament theory
Sliding filaments- 30% decrease in fiber length Explains the relationship between thick and thin filaments as contraction proceeds Cyclic process beginning with calcium release from SR Calcium binds to troponin Trponin moves, moving tropomyosin and exposing actin active site Myosin head forms cross bridge and bends toward H zone ATP allows release of cross bridge
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Figure Changes in the appearance of a Sarcomere during the Contraction of a Skeletal Muscle Fiber Figure 10.8
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Tension Created when muscles contract
Series of steps that begin with excitation at the neuromuscular junction Calcium release Thick/thin filament interaction Muscle fiber contraction Tension
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Figure 10.9 An Overview of the Process of Skeletal Muscle
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Control of skeletal muscle activity occurs at the neuromuscular junction
Action potential arrives at synaptic terminal ACh released into synaptic cleft ACh binds to receptors on post-synaptic neuron Action potential in sarcolemma
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Figure 10.10 Skeletal Muscle Innervation
Figure 10.10a, b
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Figure 10.10 Skeletal Muscle Innervation
PLAY Animation: Neuromuscular junction Figure 10.10c
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Excitation/contraction coupling
Action potential along T-tubule causes release of calcium from cisternae of SR Initiates contraction cycle Attachment Pivot Detachment Return
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Figure 10.12 The Contraction Cycle
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Figure 10.12 The Contraction Cycle
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