1. IndyCool Technologies The ultimate degree of cool. Elijah Li Victor Mateas Hoda Rifai-Bashjawish Roman Stolper Thea Zimnicki Sam Sia Faculty Advisor Elijah Li Victor Mateas Hoda Rifai-Bashjawish Roman Stolper Thea Zimnicki Sam Sia Faculty Advisor

2. Design Problem Temperature sensitive pharmaceuticals Vaccines, medicines, and diagnostics Transport The current system is ineffective Storage No energy grid in most remote areas Temperature sensitive pharmaceuticals Vaccines, medicines, and diagnostics Transport The current system is ineffective Storage No energy grid in most remote areas Reproduced from the PATH website at www.path.org, October 25, 2008. When pharmaceuticals are spoiled, there is a high expense in terms of resources and lives

3. Design Brief Develop a cooling device for transport to and/or storage in remote areas But How? Reliable cooling within required range Maintaining cooling for extended periods Self-reliant energy source Monitoring of temperature range in device Develop a cooling device for transport to and/or storage in remote areas But How? Reliable cooling within required range Maintaining cooling for extended periods Self-reliant energy source Monitoring of temperature range in device

4. Transport Background 130 million 130 million shipments of temperature sensitive pharmaceuticals each year $10,000 Cost of batch of spoiled vaccine $10,000 “Cold Chain” is a series of cold places used to store product during transport Failure when too hot or too cold Remote locations have higher chance Not always known if failure occurred

5. Storage and Dispensing Remote villages often lack a power grid “Vaccine Day” programs not effective Medications often administered by untrained personnel Trained refrigeration technicians not available Remote villages often lack a power grid “Vaccine Day” programs not effective Medications often administered by untrained personnel Trained refrigeration technicians not available

6. Competing Products http://www.sunfrost.com/vaccine_refrigerators.html http://www.coldchaintech.com/products/kooltemp-gts-120.php http://www.kodiaktech.com/FrameProducts.htm Kodiak Thermal Technologies ® ATA R36 Sun Frost ® RFVB-134a KoolTemp™ GTS-342

7. Useful Products Vial Monitor Reproduced from the PATH website at www.path.org, October 25, 2008. Temperature Assurance Vial monitors Electronic temperature monitor Cooling Instant cold packs Self cooling beer cans

8. Constraints and Specifications Consistent temperature 2-8 ºC for most pharmaceuticals Self-sufficient Self contained energy Relatively inexpensive $500-$700 Easy to use and fix No specialized knowledge Must be reliable Fool proof and damage proof Consistent temperature 2-8 ºC for most pharmaceuticals Self-sufficient Self contained energy Relatively inexpensive $500-$700 Easy to use and fix No specialized knowledge Must be reliable Fool proof and damage proof

9. Cooling AbsorptionEvaporationCompression Energy Mechanical “man” power HeatSolar power Dispenser Airtight drawers Titration device Vending machine like dispenser Monitor Temperature sensitive sticker Thermo- chromic materials Electric Material Thermal insulator Conductive barrier Vacuum or air layer

10. Design I Energy Dispenser Multiple compartments Monitor Cooling Evaporation

11. Design II Energy Heat Dispenser Titration and Vending Monitor Sticker Cooling Absorption

12. Design III Energy Solar and Mechanical Dispenser Airtight Drawers Monitor Electric Tracker Cooling Compression

13. Effective Cooling Efficient Energy IndyCool Insulative Design The Ultimate Degree of Cool

14. AcknowledgementsAcknowledgements Columbia University Biomedical Engineering Department Dr. Sam Sia Dr. Elizabeth Hillman Keith Yeager School of Engineering and Applied Science EWB: India Group EWB: Uganda Group Pfizer Ron Guido Alan McEmber Columbia University Biomedical Engineering Department Dr. Sam Sia Dr. Elizabeth Hillman Keith Yeager School of Engineering and Applied Science EWB: India Group EWB: Uganda Group Pfizer Ron Guido Alan McEmber

15. Questions?Questions?