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A Draft Sequence of the Neandertal Genome by Richard E. Green, Johannes Krause, Adrian W. Briggs, Tomislav Maricic, Udo Stenzel, Martin Kircher, Nick Patterson,

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Presentation on theme: "A Draft Sequence of the Neandertal Genome by Richard E. Green, Johannes Krause, Adrian W. Briggs, Tomislav Maricic, Udo Stenzel, Martin Kircher, Nick Patterson,"— Presentation transcript:

1 A Draft Sequence of the Neandertal Genome by Richard E. Green, Johannes Krause, Adrian W. Briggs, Tomislav Maricic, Udo Stenzel, Martin Kircher, Nick Patterson, Heng Li, Weiwei Zhai, Markus Hsi-Yang Fritz, Nancy F. Hansen, Eric Y. Durand, Anna-Sapfo Malaspinas, Jeffrey D. Jensen, Tomas Marques-Bonet, Can Alkan, Kay Prüfer, Matthias Meyer, Hernán A. Burbano, Jeffrey M. Good, Rigo Schultz, Ayinuer Aximu-Petri, Anne Butthof, Barbara Höber, Barbara Höffner, Madlen Siegemund, Antje Weihmann, Chad Nusbaum, Eric S. Lander, Carsten Russ, Nathaniel Novod, Jason Affourtit, Michael Egholm, Christine Verna, Pavao Rudan, Dejana Brajkovic, Željko Kucan, Ivan Gušic, Vladimir B. Doronichev, Liubov V. Golovanova, Carles Lalueza-Fox, Marco de la Rasilla, Javier Fortea, Antonio Rosas, Ralf W. Schmitz, Philip L. F. Johnson, Evan E. Eichler, Daniel Falush, Ewan Birney, James C. Mullikin, Montgomery Slatkin, Rasmus Nielsen, Janet Kelso, Michael Lachmann, David Reich, and Svante Pääbo Science Volume 328(5979):710-722 May 7, 2010 Published by AAAS

2 Fig. 1 Samples and sites from which DNA was retrieved. Richard E. Green et al. Science 2010;328:710-722 Published by AAAS

3 Fig. 2 Nucleotide substitutions inferred to have occurred on the evolutionary lineages leading to the Neandertals, the human, and the chimpanzee genomes. Richard E. Green et al. Science 2010;328:710-722 Published by AAAS

4 Fig. 3 Divergence of Neandertal and human genomes. Richard E. Green et al. Science 2010;328:710-722 Published by AAAS

5 Fig. 4 Selective sweep screen. Richard E. Green et al. Science 2010;328:710-722 Published by AAAS

6 Fig. 5 Segments of Neandertal ancestry in the human reference genome. Richard E. Green et al. Science 2010;328:710-722 Published by AAAS

7 Fig. 6 Four possible scenarios of genetic mixture involving Neandertals. Richard E. Green et al. Science 2010;328:710-722 Published by AAAS


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