2. Problem | Product | Market | Company | Business Model | Development | Finances | Summary ACL injuries frequent and costly: 75,000 reconstruction operations/year average cost per operation - $11,500 total cost of recovery ~ $30,000 Summary of the Problem Current rehabilitation ineffective: Re-injury and poor outcome 150X increase in re-injury after ACL reconstruction (Dunn et al. 2004) “ACL Re-injury a real worry.” – Chicago Sun Times What is the need? Phase I: Need for affordable, reliable, quantitative assessment during rehabilitation. Phase II: Minimally supervised rehabilitation program…more effective than a standard physical therapy–based program. (Grant et al. 2005)

3. Problem | Product | Market | Company | Business Model | Development | Finances | Summary Summary of the Solution Solution integrated exercise device for autonomous & affordable rehabilitation Cost Technology ~$50,000/device ~$5000/device ~$100-$150 Qualitative feedback Quantitative feedback

4. Problem | Product | Market | Company | Business Model | Development | Finances | Summary System Architecture

5. surface EMG electrode Problem | Product | Market | Company | Business Model | Development | Finances | Summary ORTHOMETRICS Bike Trainer 2007 ®

6. Problem | Product | Market | Company | Business Model | Development | Finances | Summary

7. Vastus Medialis Vastus Lateralis Problem | Product | Market | Company | Business Model | Development | Finances | Summary From Exercise and Sport Science By Donald T. Kirkendall, William E. Garrett

8. magnetic sensor Problem | Product | Market | Company | Business Model | Development | Finances | Summary

10. bluetooth user interface Problem | Product | Market | Company | Business Model | Development | Finances | Summary

12. Market Portable EMG Designed for unconstrained, non-repeatable motion Nike/Ipod Delsys Myomonitor Integrated Exercise Too expensive OR Too simple Orthometrics Bike Trainer Biodex System 4

13. Problem | Product | Market | Company | Business Model | Development | Finances | Summary Company Overview Our Mission Empower users with biofeedback Our Product A simple, affordable system Our Advantage Integration of existing components Rapid development time Rapid market entry Reduce rehab costs by 75% (Schenck et al. 1997) http://redmondpt.com/Redmond%20Physical%20Therapy%20gym.jpg http://www.biopac.com/ProductImages/tel100crfb600.gif

14. Problem | Product | Market | Company | Business Model | Development | Finances | Summary Business Model

15. Short term considerations Acquire funding from various sources Angel investors, venture capitalists, donations, loans, rentals Major costs of operations Research and development ($100,000s) Legal costs ($100,000s) Clinical trials ($100,000s- low $1,000,000s) http://www.leefalin.com/wp-images/acl.jpg R & D, Prototype Clinical trials Lease & FDA Home-use Sales Year: 2008 2009-2010 2010 2011 2012 New product Phase I Phase II and III Problem | Product | Market | Company | Business Model | Development | Finances | Summary Short Term Goals

16. Product Improvement Incorporate Wireless Data Collection Greater freedom of motion More flexible placement and spacing of electrodes Refine signal processing Cleaner data, less noise Based on clinical trials R & D, Prototype Clinical trials Lease & FDA Home-use Sales Year: 2008 2009-2010 2010 2011 2012 New product Phase I Phase II and III Problem | Product | Market | Company | Business Model | Development | Finances | Summary Long Term Goals Product Innovation Phase 2 Integrated product for Home Use Wireless transmission of workout data to online server Phase 3 Expansion to other exercise modalities and other patient populations.

17. Problem | Product | Market | Company | Business Model | Development | Finances | Summary Cost Projections ComponentSupplierPriceQuantityCost stationary bicycleSears$179.951 surface electrodes (reusable, 3' lead) Jari Supply$29.502$59.00 goniometers*Rehab Outlet$55.002$110.00 knee cuffs*Allegro Medical$45.001 bluetooth USB adaptor*D-Link$49.991 GOULD ECG/Biotach Signal Acquisition System Ugrad wet labborrow1- National Instruments analog to digital peripheral board Ugrad wet labborrow1- Laptop PC running MATLAB Ugrad wet labborrow1- magnetic cadence monitor for bike Chris O’Conorborrow1- Total Cost$443.94 *future add-ons

18. Problem | Product | Market | Company | Business Model | Development | Finances | Summary Summary Orthometrics: Tomorrow’s Solution to Today’s Rehabilitation Needs Why choose the Orthometrics Bike Trainer? Why choose the Orthometrics Bike Trainer? Reliable, Accurate, and Safe Closed kinetic chain Seamless integration of diagnostic sensors and exercise module Reduces cost of rehab Tracks recovery Monitors compliance Speeds up recovery Improves outcome. Reliable, Accurate, and Safe Closed kinetic chain Seamless integration of diagnostic sensors and exercise module Reduces cost of rehab Tracks recovery Monitors compliance Speeds up recovery Improves outcome.

19. Dr. William Macaulay Orthopedic Surgeon, Columbia University Medical Center Director of Center for Hip and Knee Replacement Dr. Ranjan Gupta Department Chair of Orthopaedic Surgery, UC Irvine Professor of Orthopaedics, Anatomy & Neurobiology, and BME James Gossett Associate Athletic Director, Columbia University Dr. Evan Johnson Director of Physical Therapy at the Spine Center Administrative Director of the Spine Center Julianne Costa Occupational Therapist Registered Physical Therapist Dr. Tim Wright Orthopaedic Biomechanics and Biomaterials Hospital of Special Surgery Thank You Dr. Clark Hung Associate Professor of Biomedical Engineering Dr. Elizabeth Hillman Assistant Professor of Biomedical Engineering Keith Yeager Senior Staff Associate, Laboratory Manager Sean Burgess Teaching Assistant