1. System Design for CDEM

2. Browser-based UI Tomcat Web Server JSP Application Computing Engine QueriesResult Pages Results Remote Function Calls HTTP RMI UI related, Input/Output Image preprocessing, Feature extraction, Random walk

3. System Balance

4. Browser-based UI Tomcat Web Server JSP Application Computing Engine k QueriesResult Pages Results Remote Function Calls HTTP RMI UI related, Input/Output Image preprocessing, Feature extraction, Random walk Computing Engine 1 ……

5. Workflow for Query

6. User Preprocessing Image Aligned, Morphed Feature Extraction PCA/ICA/ Wavelets Graph Augment Edge weighted graph Proximity Computing: RWR keyword, gene query In-system image query. Combined query

7. Query and Retrieval Model

8. Images Genes Keywords fj (CG10917) insitu1234.jpg embryonic hindgut