1. Happy Tuesday! Bellwork: 2. 1. READ THE DIRECTIONS! Quick Write: Analyze the diagrams to the left. In 30 words or more use evidence FROM YOUR NOTES to justify what process is going on in picture one and picture two.

2. Today’s Standard: (B.6H) describe how techniques such as…chromosomal analysis are used to study the genomes of organisms Essential Question: How can we apply karyotypes to the real world?

3. Chromosomes: coiled DNA located in the cell nucleus. An organism inherits one of each chromosome from each parent. Homologous chromosomes = 2 copies of each chromosome

4. Before After A karyotype is a picture of a person's chromosomes. In order to get this picture, the chromosomes are isolated, stained, and examined under the microscope. A picture is taken. Then, the picture is cut up and rearranged by the chromosome’s size. The chromosomes are lined up from largest to smallest. A trained cytogeneticist can look for missing or extra pieces of chromosome.

5. Words you’ll need to know Somatic Cells = Body Cells = Diploid Gametes = Sex Cells = Haploid Trisomy = organism has an extra chromosome Monosomy = organism is missing a chromome Nondisjunction = chromosomes fail to split during meiosis

6. Average Karyotype (Male)

7. Time to Analyze… In the next few slides…something is NOT “normal” Can you spot it?

24. To get started… 1.Fill in your name on your form 2.Make sure your patient’s karyotype matches the handout (A,B,C). 3.There is allot to do today. You must use teamwork to be successful today. 1.For example…while one person is cutting/pasting another should be completing the questions/answer section. 2.You MUST ask questions if you get stuck.

25. Your task: 1.Cut and match your patients chromosomes to complete the Karyotype 2.Use the Karyotype information to answer questions about your patient and to determine what disorder your patient may have.

26. Turn in your paper to me before you leave today.

27. Websites to Use: www.mayoclinic.org www.genome.gov/10001204 http://www.nlm.nih.gov/medlineplus/geneticdisorders.html