1. Day DateSubjectTo be read prior to this class period:... M1/21no class – Rev. Martin Luther King, Jr. Day W1/23Water and the Chemical Environment Chapter 2 (except pp30-35) M1/28Quiz #1 on Ch. 1 and parts of Ch. 2 and related lectures/handouts (no make ups for missed quiz) Cell Membranes Chapter 6 W1/30Macromolecules Chapter 3 (except pp63-69) M2/4Macromolecules W2/6Quiz #2 on Ch. 3 and 6 and related lectures/handouts (no make ups for missed quiz) The CellChapter 7 M2/11Bioenergetics W2/13Cell Respiration Chapter 9 M2/18no class - Winter Break W2/20no class - Winter Break M2/25EXAM I Chapters 1, 6,7, parts of 2, 3 REMEMBER to bring your notes from one lecture to hand in at the exam. (worth 10%).

2. 1) All living things are composed of cells* 2) All cells come from pre-existing cells* * The Cell Theory 3) All cells exist in a water environment 4) All cells are bounded by a membrane 5) All cells have similar chemistrys (proteins, proteins, proteins) 6) DNA is the primary heritable molecule (DNA’s BIG job is to code for proteins) 7) The concept of gene regulation and totipotency

3. Some examples of endocytosis and exocytosis: 1) Aquaporin-2 in human kidney cells 2) neurotransmitter vesicles in all human nerve cells 3) phagocytosis of bacteria by human white blood cells 4) receptor-mediated endocytosis and cholesterol traffic in humans membrane traffic in cells

4. Some examples of endocytosis and exocytosis: 1) Aquaporin-2 in human kidney cells 2) neurotransmitter vesicles in all human nerve cells 3) phagocytosis of bacteria by human white blood cells 4) receptor-mediated endocytosis and cholesterol traffic in humans membrane traffic in cells

7. Low-density lipoprotein (LDL) belongs to the lipoprotein particle family. Diameter is about 22 nm, Mass is about 3 million Daltons (one Hydrogen atom = 1 Dalton) But vary in size (A few large LDL are healthier than many small LDL.) Each LDL contain: 1) one B-100 protein molecule (It’s big: 4536 amino acid residues) B-100 binds to the LDL receptor on cells. 2) a highly-hydrophobic core consisting of linoleate, a fatty acid, and about 1500 cholestrol molecules 3) surrounded by a shell of phospholipids

10. HDL is “good cholesterol” and carries excess cholesterol from our cells back to the liver. Liver cells have an HDL receptor.

11. More from Chapter 6: “The Cell”

15. The cytoskeleton has three main components We will one job of each of the three.