1. First Author: Ráduly Kinga Author: Ráduly Orsolya Coordinators: Dr. Zaharia Kézdi Iringo, Dr. Nina Sincu

2.  APACHE II was designed to measure the severity of disease for adult patients admitted to Intensive care units, for patients aged 15 or older.  This scoring system is used in many ways:  can be used to describe the morbidity of a patient when comparing the outcome with other patients  predicted mortalities are averaged for groups of patients in order to specify the group’s morbidity.

3.  The Estimated Risk of Hospital Death (ERHD), based on APACHE II score: - > 35% for APACHE II score > 20 pt - 11-35% for APACHE II score of 10-20 pt - < 11% for APACHE II score < 10 pt

4.  We have conducted a retrospective, descriptive, transversal study on a sample of 29 patients admitted to Infectious Diseases Clinic I from Tg-Mures, during 2009-2010.  The study included patients aged 16 or older, diagnosed with an infectious disease, who required intensive care treatment.  We analyzed the patients’ files and calculated the APACHE II score.  The results were analyzed by using a statistic programme (GraphPad)

6. Age over ≥ 65 years: 6 out of 8 patients have deceased (75%) < 65 years: 9 out of 21 patients (42.85%) P 0.2148 - we did not find statistically significant association RR: 1.750 CI 95%= 0.9267-3.305

8. Mortality rate: - 84.16% for APACHE II > 20 pt - 30.76% - APACHE II 10- 20 pt - 0% - APACHE II < 10 pt

12.  The mortality rate was higher than expected in patients with APACHE II score > 20 pt (84.16 % compared with an ERHD > 35 %)  We did not find statistically significant association between advanced age (over 65 years old) and mortality rate (p=0.2148).  The severe illnesses, such as severe sepsis and respiratory impairment were associated with worse outcome.