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Published byRosemary Dalton Modified over 9 years ago
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DNA, RNA and PROTEIN SYNTHESIS
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WHAT MAKES UP DNA? IT IS A MOLECULE COMPOSED OF CHEMICAL SUBUNITS CALLED NUCLEOTIDES
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NUCLEOTIDES ARE COMPOSED OF THREE SUBUNITS A FIVE CARBON SUGAR A PHOSPHATE GROUP A NITROGEN- CONTAINING BASE
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NITROGENOUS BASES THERE ARE FOUR NITROGENOUS BASES IN DNA ADENINE CYTOSINE THYMINE GUANINE
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ADENINE AND GUANINE ARE PURINES THEY ARE MADE OF TWO RINGS OF NITROGEN AND CARBON ATOMS
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THYMINE AND CYTOSINE ARE PYRIMIDINES THEY CONTAIN A SINGLE RING OF CARBON AND NITROGEN ATOMS
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THE DNA HAS TWO MAIN SIDES THE SIDES ARE LIKE THE UPRIGHT PARTS OF A LADDER THE SIDES ARE MADE OF THE SUGAR AND THE PHOSPHATE GROUP (ACID)
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THEY ALTERNATE ALONG THE SIDES THE RUNGS OF THE LADDER ARE MADE OF NITROGEN BASES THERE ARE WEAK HYDROGEN BONDS BETWEEN THE BASE PAIRS
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BASE-PAIRING RULES A PURINE ALWAYS PAIRS WITH A PYRIMIDINE THE STRICTNESS OF BASE PAIRING RULES PRODUCES COMPLIMENTARY BASE PAIRS
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ADENINE BONDS WITH THYMINE CYTOSINE BONDS WITH GUANINE
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THE ARRANGEMENT OF NUCLEOTIDES IS WHAT MAKES US DIFFERENT
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DNA REPLICATION DNA MUST MAKE AN IDENTICAL COPY OF ITSELF DURING REPLICATION
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DNA HELICASES (ENZYME) BREAKS THE HYDROGEN BONDS BETWEEN THE NITROGEN BASES THE MOLECULE BEGINS TO UNWIND
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ONCE STRANDS ARE SEPARATED, PROTEINS ATTACH TO EACH STRAND TO HOLD THEM APART AREAS WHERE THE DOUBLE HELIX SEPARATE ARE CALLED REPLICATION FORKS
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DNA POLYMERASE (ENZYME) SWEEPS ALONG BONDING NEW NUCLEOTIDES TO EACH SIDE OF THE PARENT CHAIN
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THE PROCESS CONTINUES UNTIL ALL DNA HAS BEEN COPIED TWO NEW IDENTICAL DNA MOLECULES ARE FORMED
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DNA POLYMERASE “PROOF-READS” THE STRAND NUCLEOTIDES ARE ADDED AND INCORRECT ONES ARE CORRECTED
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RNA A NUCLEIC ACID FOUND IN THE NUCLEUS AND CYTOPLASM COMPOSED OF A SINGLE CHAIN OF NUCLEOTIDES CONTAINS RIBOSE
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CONTAINS URACIL INSTEAD OF THYMINE
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TRANSCRIPTION THE INSTRUCTIONS FOR MAKING A PROTEIN ARE TRANSFERRED FROM A GENE TO AN RNA MOLECULE WE CALL THIS PROCESS TRANSCRIPTION
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TRANSCRIPTION EVENTS FORMATION OF RNA RNA POLYMERASE BONDS TO THE START SIGNAL OF DNA THE DOUBLE HELIX UNWINDS
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RNA POLYMERASE ADDS AND LINKS COMPLEMENTARY NUCLEOTIDES TO THE DNA TEMPLATE WITH COVALENT BONDS RNA MATCHES UP UNTIL A STOP SIGNAL IS REACHED
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THE SINGLE-STRANDED MOLECULE BREAKS AWAY FROM THE DNA CHAIN THE DOUBLE HELIX REFORMS
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THE RNA FORMED IS CALLED MESSENGER RNA (mRNA) mRNA CODES FOR PROTEIN PRODUCTION THE mRNA LEAVES THE NUCLEUS AND GOES TO THE RIBOSOME
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CODING FOR PROTEINS 3 BASES IN A ROW CODES FOR A PARTICULAR AMINO ACID (CODON) MORE THAN ONE SET OF CODES CAN REPRESENT AN AMINO ACID
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THERE ARE STOP CODONS THAT DO NOT CODE FOR AN AMINO ACID THEY READ ONLY IN ONE DIRECTION THE CODE IS UNIVERSAL FROM ORGANISM TO ORGANISM
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TRANSLATION THE PROCESS BY WHICH THE INSTRUCTIONS ON THE RNA MOLECULE ARE READ AND AN AMINO ACID CHAIN (PROTEIN) IS PRODUCED
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TRANSFER RNA (tRNA) TEMPORARILY CARRIES A SPECIFIC AMINO ACID PROTEINS ARE MADE OF CHAINS OF AMINO ACIDS TRANSLATION
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AN ANTICODON IS A THREE-NUCLEOTIDE SEQUENCE ON A tRNA THAT IS COMPLEMENTARY TO AN mRNA CODON RIBOSOMAL RNA MOLECULES AND PROTEINS MAKE UP RIBOSOMES
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THE CYTOPLASM CONTAINS THOUSANDS OF RIBOSOMES EACH RIBOSOME TEMPORARILY HOLDS ONE mRNA AND TWO tRNA MOLECULES
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STEP 1 mRNA WITH THE START CODON “AUG” BINDS TO THE ANTICODON OF TRNA CONTAINING METHIONINE
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STEP 2 THE tRNA WITH THE COMPLEMENTARY ANTICODON BONDS TO THE NEXT CODON.
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STEP 3 ENZYMES FORM A PEPTIDE BOND BETWEEN THE ADJACENT AMINO ACIDS
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STEP 4 THE MOLECULES THEN MOVE AS A UNIT AND THE NEW CODON RECEIVES THE NEXT TRNA AND ITS AMINO ACID STEP 5 THE AMINO ACID BONDS TO THE GROWING PROTEIN CHAIN
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STEPS 2 THOUGH 5 CONTINUES UNTIL A “STOP” CODON IS REACHED
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