1. ILLNESSES OF SALIVARY GLANDS, LIPS, TONGUE & MOUTH CAVITY
Associate-prof. V.Voloshyn
According prof. Pospishil O.V.& prof. Strukov A.I.

2. ILLNESSES OF SALIVARY GLANDS
innate (congenital):
agenesia, hypogenesia, octopia, hypertrophy of glands, additional glands;
imperforation of channels, narrowing or atresia, anomalous branches out, defects of walls with formation of fistulas;
acquired:
sialoadenitis, sialoalitiasis, cysts, tumours and tumular processes. 2

3. Sialoadenitis classification
primary (independent disease);
secondary (complication or displays of other disease)
(B)
Acute;
Chronic;
Chronic with acuting 3

4. Etiology of Sialoadenitis
Microbes
Viruses
Autoimmune process 4

5. EPIDEMIC PAROTITIS
RNA virus – mixovirus group

6. CYTOMEGALIA
owl eye
DNA virus – herpes group

7. AUTOIMMUNE SIALOADENITIS
Sjogren’s disease
Mikulich’s disease
dry keratoconjunctivitis;
xerostomia;
rheumatic arthritis.
xerostomia;
xerophtalmia.

8. Pathoanatomy of Sialoadenitis
Acute sialoadenitis:
serosal, purulent (local or diffuse);
gangrenous;
Chronic sialoadenitis:
productive
intermediate 8

9. Purulant Sialoadenitis
Chronic Sialoadenitis

10. Complication and consequences of Sialoadenitis
Acute sialoadenitis → convalescence or chronic prss;
Chronic → sclerosis (cirrhosis) of gland with atrophy of acinus portion, stromal lipomatosis with the decline or function loss ;
→ xerostomia.
sclerosis of gland 10

11. SIALOLITHIASIS
The concrements, which present in a gland and more frequent in its channels are the basis of the disease.
More frequently the stones appear in a submandibular gland; stones appear in parotid rarely; sublingual gland is almost never damaged. The men of middle ages ill mainly 11

12. Etiology and pathogeny
Etiology and pathogeny. The gland channels dyskinesia, their inflammation, stagnation and saliva alkalining, increase of its viscidity, extraneous bodies penetration in the channels are the reasons of salivary stone formations. These factors are instrumental in falling out from saliva of the various salts (calcium phosphate, calcspar) with crystallization them on organic basis — matrix (ephithelial cells rejection, mucin) 12

13. Pathoanatomy. The formed stones have different sizes (from sands to 2 centimeters in a diameter), shapes (oval or oblong), colors (grey, yellow), consistencies (soft, densed). The acute inflammation (sialodochitis) appears at the channel obturation. Very often festering sialoadenitis develops. Sialoadenitis became chronic with the periodic acuteening afterwards.
Complication and consequences. The sclerosis (cirrhosis) of gland develops at chronic motion of sialoadenitis. 13

14. ADENOCELES
Adenoceles more often arise up in the small glands. The reasons of the cysts formations are trauma, channels inflammations with subsequent (послідуючим) sclerosis and obliteration. The sizes of cysts are different. Cysts with mucus or mucoid component are named mucocele. 14

15. TUMOURS
The tumours of salivary glands formed 6% in relation to all tumours which develop in a human; in stomatological oncology they make a greater particle (portion). 15

16. Classification of salivary glands tumors (World Health Protection Organozation):
Adenomas: pleomorphic (polymorphic), monomorphic (oxyphilic, adenolimphoma, other types).
Mucoepidermoid tumour.
Acinocell tumour.
Carcinoma: adenoceles, adenocarcinoma, epidermoid undifferentiated carcinoma in a polymorphic adenoma (the malignant mixed tumor). 16

17. Pleomorphic (polymorphic) adenoma:
is most widespread of salivary glands ephithelial tumours. Formed near 50% tumours of this localization. Almost 90% of cases they are in a parotid gland.
Macroscopically: round or oval nodes, sometimes hilly, dense or elastic consistency, up to 5-6 cm in diameter. Tumor are surrounded by a thin capsule. The tissue is whitish, often with mucose and cysts. 17

18. Pleomorphic adoma
Can be quite varied. Epithelial cells in the tumor may be rounded, polygonal, cubic, cylindrical and form as channel, solid fields, some nest tending. Cells of myoepithelium with light cytoplasm. Mucoid, mixoid and chondroid tissue areas. Hyalinosis, epidermidalization and keratosis present. 18

19. A monomorphic adenoma Histological classification:
is the bening tumour of salivary glands (1—3%); it is localized mainly in a parotid gland. A tumour grows slowly
Histological classification:
oxyphilic;
adenolymphomas;
basal cells;
light cells;
mucoepidermal adenomas 19

20. Oxiphilic adenoma (onkocytomas)
Are formed by large cells with small grains in a cytoplasm. Localized mainly in the parotid glands. The cells are placed in a solid field. 20

21. ADENOLIMPHOMAS 21

22. MUCOEPIDERMAL ADENOMAS22

23. A) THE MALIGNANT EPHITHELIAL TUMOURS OF SALIVARY GLANDS
B) THE TUMULAR DISEASES -limphoepitelial defeat; -sialosis; -oncocytosis (at adults). 23

24. DISEASES OF LIPS, TOUNGE AND SOFT TISSUE OF MOUTH CAVITY
Cheilitis:
exfoliatic;
glandular;
contactic;
meteorological (actinic);
granulomatic (at Melcerson-Rosental syndrom);
Cheilitis of Manganotti;
inflammation of mouth corners;
furuncle of lips;
erysipelas (rose) 24

25. GLOSSITIS desquamative glossitis; diamond-shaped glossitis;
black pilose tongue;
chronic glossitis. 25

26. STOMATITIS (select next groups):
traumatic;
infectious;
allergic;
as a result of exogenous intoxications;
at somatic illnesses;
at dermatosiss 26

27. HERPETIC STOMATITIS 27

28. CANDIDAL STOMATITIS
Tubular hyphens (9.3) 28

29. Pre-tumours changes leuoplacy; erytroplacy; chailitis of Manganotti.29

30. LEUOPLACY (9.4) 30

31. LEUOPLACY (9.5, 9.6) 31

32. VILLOMA 32

33. FLAT-CELLS CANCER (9.8; 9.9) 33

34. CANCER IN SITU (9.10) 34

35. FLAT-CELLS KERATOSIC CANCER (9.11)35

36. FLAT-CELLS unKERATOSIC CANCER (9.12)36

37. Thank you for attention!