1. Retinoblastoma By Nathan Raine and Max Barna

2. What is Retinoblastoma? Retinoblastoma is a type of cancer that forms on the eyes. Retinoblastoma is caused by a deletion of chromosomes 13, 14, 15, 21, and 22. This is a frameshift mutation.

3. How can you get it? Eye color is the gene that can code for retinoblastoma. Children age six are most affected. Retinoblastoma is a cancer but has no carcinogens so receiving it is completely genetic (X-linked).

4. What are the symptoms? The pupil may appear white at certain angles. Most are cross-eyed with poor vision. Eventually, if not treated, a tumor will form on the eye.

5. What is the treatment? Without a tumor or a small tumor, retinoblastoma is cured by simple means of laser eye surgery. With a large tumor, Chemotherapy will be needed as well as laser eye surgery.

6. Odds Luckily, retinoblastoma has a 95- 98% cure rate. Most that were not cured were the only to die from retinoblastoma. No matter how severe, all types of retinoblastoma can be cured. Only 2% of all who are cured become blind after treatment.

7. Other Information Retinoblastoma is part of the deletion of 5 chromosomes which makes it extremely unlikely. If you are older than 19, you cannot be diagnosed with retinoblastoma because your eyes stop developing at age 19. Two organization websites for more info: http://www.ncbi.nlm.nih.gov/pubmedhealt h/PMH0002025/http://www.ncbi.nlm.nih.gov/pubmedhealt h/PMH0002025/, http://ghr.nlm.nih.gov/condition/retinobla stoma http://ghr.nlm.nih.gov/condition/retinobla stoma http://www.ncbi.nlm.nih.gov/pubmedhealt h/PMH0002025/ http://ghr.nlm.nih.gov/condition/retinobla stoma

8. Photos of Retinoblastoma Photo of retinoblastoma www.geneticpeople.com www.geneticpeople.com Karyotype of person affected by retinoblastoma. www.haligonia.com