1. Steps of Respiration/Metabolism 1. Glycolysis (O2 or -O2) 2. Pyruvate->Acetyl CoA (O2) or Fermentation (-O2) 3. Krebs Cycle/TCA Cycle/Citric Acid Cycle (O2) 4. Electron Transport Chain/Oxidative (O2) Phosphorylation

2. Steps of Respiration/Metabolism 1. Glycolysis (O2 or -O2) 2. Pyruvate->Acetyl CoA (O2) or Fermentation (-O2) 3. Krebs Cycle/TCA Cycle/Citric Acid Cycle (O2) 4. Electron Transport Chain/Oxidative (O2) Phosphorylation

3. Fermentation (-O2)

7. SUMMARY OF GLUCOSE OXIDATION Mitochondrion Glucose 2 NADH 2 Pyruvate Cytoplasm 2 ATP Pyruvate->Acetyl CoA (O2)

8. Pyruvate Dehydrogenase Multienzyme Complex

9. Pyruvate->Acetyl CoA (O2)

11. SUMMARY OF GLUCOSE OXIDATION Mitochondrion Glucose 2 NADH 2 Pyruvate Cytoplasm 2 ATP Pyruvate->Acetyl CoA (O2)

12. SUMMARY OF GLUCOSE OXIDATION Mitochondrion 2 Acetyl CoAGlucose 2 NADH 2 CO2 2 Pyruvate Cytoplasm 2 ATP 2 NADH Where do we go next?

13. SUMMARY OF GLUCOSE OXIDATION Mitochondrion 2 Acetyl CoAGlucose 2 NADH 6 NADH 2 FADH2 2 ATP 2 CO2 4 CO2 2 Pyruvate KREBS CYCLE Cytoplasm 2 ATP 2 NADH Krebs Cycle/TCA Cycle/Citric Acid Cycle (O2)

14. 14

15. OK, but where do elements come from? Sodium Potassium Nitrogen Sulfur Hydrogen Iron Chlorine Calcium Manganese 15