1. Biomedical Research Methods
Biomedical Technology
Unit 10.02

2. Chemical, Mechanical, Mathematical, and Computer Simulations
Strengths of models
Limitations of models

3. In Vitro Tests “In Glass”
Takes place in an artificial environment
Strengths of in vitro studies
Limitations of in vitro studies

4. Non-human Models
Animals provide the best known surrogate for humans in the lab
Similarities between animals and humans outweigh differences
Strengths of animal models
Limitations of animal models

5. Human Studies Most often used in developing prescription drugs
Three major phases of clinical trials
After clinical trials
Strengths of clinical trials
Actual human data
Limitations of clinical trials

6. Epidemiological Studies
Experimental epidemiology
Descriptive
Observational
Information gathering occurs after the fact

7. Epidemiological Studies
They do not demonstrate a direct cause and effect, but instead show a statistically significant association between exposure and disease
Strengths of epidemiological studies
Limitations of epidemiological studies